News Column

Research Conducted at Shanghai University Has Provided New Information about Gold Nanoparticles

June 27, 2014

By a News Reporter-Staff News Editor at Science Letter -- Current study results on Gold Nanoparticles have been published. According to news reporting from Shanghai, People's Republic of China, by NewsRx journalists, research stated, "In this paper, we report a novel colorimetric strategy for the detection of small molecules by using Pb2+ ion as an example. In this strategy, DNAzyme duplex modified gold nanoparticles (GNPs) are designed to be unable to interact with graphene oxide (GO)."

The news correspondents obtained a quote from the research from Shanghai University, "However, in the presence of Pb2+, the substrate strand of the DNAzyme is cleaved at its cleavage site, resulting in the disassembly of the DNAzyme duplex modified GNPs into three parts, i.e., the 3'-and 5'-fragments of substrate strand and the DNAzyme strand modified GNPs. By taking advantage of the efficient cross-linking effect of ssDNA-GNPs to GO, colorimetric sensor for the detection of the metal ion can be fabricated with a detection limit of 100 pM, which is much lower than the previous reports."

According to the news reporters, the research concluded: "This colorimetric method has also been used for the determination of Pb2+ in the tap water of the local city and the water from a reservoir with satisfactory results, so it may have potential applications in the future."

For more information on this research see: Ultrasensitive detection of lead ion based on target induced assembly of DNAzyme modified gold nanoparticle and graphene oxide. Analytica Chimica Acta, 2014;831():60-64. Analytica Chimica Acta can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier -; Analytica Chimica Acta -

Our news journalists report that additional information may be obtained by contacting C. Li, Shanghai Univ, Sch Life Sci, Lab Biosensing Technol, Shanghai 200444, People's Republic of China. Additional authors for this research include L.M. Wei, X.J. Liu, L. Lei and G.X. Li (see also Gold Nanoparticles).

Keywords for this news article include: Asia, Shanghai, Nanotechnology, Gold Nanoparticles, Emerging Technologies, People's Republic of China

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Science Letter

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