News Column

Research Conducted at RIKEN Has Updated Our Knowledge about Macromolecular Research

June 27, 2014

By a News Reporter-Staff News Editor at Science Letter -- Researchers detail new data in Macromolecular Research. According to news reporting out of Saitama, Japan, by NewsRx editors, research stated, "Medical advances have prompted the research and development of biomaterials. Especially, chitosan has emerged as new generation of biomaterials because it beneficial properties as a natural polymer, such as less toxic, biodegradable, and biocompatible than synthetic ones."

Our news journalists obtained a quote from the research from RIKEN, "The prepared azidophenyl O-carboxymethyl chitosan (Az-O-CMC) was characterized by FTIR, H-1 NMR and particle-size analyzer. The hardening rate and cross-linking maintenance of the Az-O-CMC were investigated with its irradiation time and concentration. A photo-mask was used for observation of photoimmobilization. 3T3-L1 cells were cultured to determine effect of cytotoxicity. Protein release test was conducted to evaluate the immobilizing effect. In addition, animal test was investigated for wound healing application."

According to the news editors, the research concluded: "In this study, the results indicate that immobilization of protein with Az-O-CMC will be useful for medical application."

For more information on this research see: Preparation and in vivo evaluation of photo-cured O-carboxymethyl chitosan micro-particle for controlled drug delivery. Macromolecular Research, 2014;22(5):541-548. Macromolecular Research can be contacted at: Polymer Soc Korea, Room 601, Hatchon Building, 831 Yeoksam-Dong, Kangnam-Ku, Seoul 135-792, South Korea. (Springer -; Macromolecular Research -

Our news journalists report that additional information may be obtained by contacting Y. Heo, RIKEN Adv Sci Inst, Nano Med Engn Lab, Wako, Saitama 3510198, Japan. Additional authors for this research include S.H. Park, S.Y. Seo, J.Y. Yun, Y. Ito and T.I. Son (see also Macromolecular Research).

Keywords for this news article include: Asia, Japan, Saitama, Macromolecular Research

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Science Letter

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