News Column

New Capillary Electrophoresis Findings from J. You et al Outlined

June 27, 2014



By a News Reporter-Staff News Editor at Science Letter -- Current study results on Capillary Electrophoresis have been published. According to news reporting out of Shenzhen, People's Republic of China, by NewsRx editors, research stated, "Gold nanoparticles (Au NPs) were synthesized and stabilized by using water-soluble quaternized cellulose (QC) as support matrix through a straightforward and environmentally friendly aqueous-phase approach. The structure and morphology of QC-supported Au NPs (QC-Au NPs) were investigated systematically by UV-visible, FT-IR, x-ray diffraction and TEM measurement."

Our news journalists obtained a quote from the research, "The Au NPs with mean diameter of about 7 nm were shown to efficiently redisperse in water due to the strong interaction between QC and Au NPs, and the solutions were quite stable after storage for nearly 4 months at room temperature. QC-Au NPs were subsequently used as novel physically adsorbed coatings for protein separation by CE. The separation performance was significantly improved in the capillary coated by QC-Au NPs compared with that of the uncoated capillary or QC coated capillary. A small quantity of Au NPs (Au content of 4.6%) was adequate for the obvious improvement of coating ability. The theoretical plate number of lysozyme in QC-Au1 NPs coated capillary was 2.9 times as much as that in QC coated capillary. We have demonstrated the separation of six model proteins with RSD of migration time less than 2.79% and RSD of peak area less than 4.81%. Furthermore, QC-Au NPs was applied to the analysis of closely related proteins and biological samples."

According to the news editors, the research concluded: "With simplicity, high resolution and reproducibility, the proposed method shows potential for applications in proteomics and clinical diagnosis."

For more information on this research see: Quaternized cellulose-supported gold nanoparticles as capillary coatings to enhance protein separation by capillary electrophoresis. Journal of Chromatography A, 2014;1343():160-166. Journal of Chromatography A can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands. (Elsevier - www.elsevier.com; Journal of Chromatography A - www.elsevier.com/wps/product/cws_home/502688)

Our news journalists report that additional information may be obtained by contacting J. You, Center Dis Prevent & Control Futian Dist, Shenzhen 518040, People's Republic of China. Additional authors for this research include L.G. Zhao, G.W. Wang, H.T. Zhou, J.P. Zhou and L.N. Zhang (see also Capillary Electrophoresis).

Keywords for this news article include: Asia, Shenzhen, Nanoparticle, Nanotechnology, Emerging Technologies, Capillary Electrophoresis, People's Republic of China

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Science Letter


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