News Column

UNIST Details Findings in Nanocomposites

June 24, 2014



By a News Reporter-Staff News Editor at Cancer Weekly -- Current study results on Nanocomposites have been published. According to news reporting from Ulsan, South Korea, by NewsRx journalists, research stated, "Genetic and chemical engineering approaches are used to employ P22 viral capsids as nanoplatforms for developing an efficient delivery vehicle."

The news correspondents obtained a quote from the research from UNIST, "Catechol ligands are chemically attached to the interior surface of P22 viral capsid for subsequent encapsulation of an anticancer drug, bortezomib (BTZ), through boronic acid-diol complexation. For targeted delivery, hepatocellular carcinoma (HCC)-targeting peptide (SP94, SFSIIHTPILPL) is synthesized and chemically conjugated to the exterior surface of the P22 viral capsid nanocomposites."

According to the news reporters, the research concluded: "Effective targeted delivery of synthesized P22 viral capsid nanocomposites is demonstrated by fluorescent cell imaging and the efficacy of delivered P22 viral capsid nanocomposites is evaluated using a cell viability assay."

For more information on this research see: Development of P22 Viral Capsid Nanocomposites as Anti-Cancer Drug, Bortezomib (BTZ), Delivery Nanoplatforms. Macromolecular Bioscience, 2014;14(4):557-564. Macromolecular Bioscience can be contacted at: Wiley-V C H Verlag Gmbh, Boschstrasse 12, D-69469 Weinheim, Germany. (Wiley-Blackwell - www.wiley.com/; Macromolecular Bioscience - onlinelibrary.wiley.com/journal/10.1002/(ISSN)1616-5195)

Our news journalists report that additional information may be obtained by contacting J. Min, UNIST, Sch Nanobiosci & Chem Engn, Ulsan 689798, South Korea. Additional authors for this research include H. Moon, H.J. Yang, H.H. Shin, S.Y. Hong and S. Kang (see also Nanocomposites).

Keywords for this news article include: Asia, Ulsan, Cancer, Genetics, Oncology, South Korea, Nanoplatforms, Nanotechnology, Emerging Technologies

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Cancer Weekly


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