News Column

Study Data from National Brain Research Center Provide New Insights into Peptides and Proteins

June 24, 2014

By a News Reporter-Staff News Editor at Life Science Weekly -- Researchers detail new data in Proteins. According to news reporting originating from Gurgaon, India, by NewsRx correspondents, research stated, "Inhibition of amyloid fibrillation and clearance of amyloid fibrils/plaques are essential for the prevention and treatment of various neurodegenerative disorders involving protein aggregation."

Our news editors obtained a quote from the research from National Brain Research Center, "Herein, we report curcumin-functionalized gold nanoparticles (Au-curcumin) of hydrodynamic diameter 10-25nm, which serve to inhibit amyloid fibrillation and disintegrate/dissolve amyloid fibrils. In nanoparticle form, curcumin is water-soluble and can efficiently interact with amyloid protein/peptide, offering enhanced performance in inhibiting amyloid fibrillation and dissolving amyloid fibrils."

According to the news editors, the research concluded: "Our results imply that nanoparticle-based artificial molecular chaperones may offer a promising therapeutic approach to combat neurodegenerative disease."

For more information on this research see: Inhibition of Amyloid Fibril Growth and Dissolution of Amyloid Fibrils by Curcumin-Gold Nanoparticles. Chemistry-A European Journal, 2014;20(20):6184-6191. Chemistry-A European Journal can be contacted at: Wiley-V C H Verlag Gmbh, Boschstrasse 12, D-69469 Weinheim, Germany (see also Proteins).

The news editors report that additional information may be obtained by contacting S. Palmal, Natl Brain Res Center, Manesar 122050, Gurgaon, India. Additional authors for this research include A.R. Maity, B.K. Singh, S. Basu, N.R. Jana and N.R. Jana.

Keywords for this news article include: Asia, India, Gurgaon, Amyloid, Proteins, Nanotechnology, Gold Nanoparticles, Emerging Technologies

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Life Science Weekly

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