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Studies from Rabin Medical Center Have Provided New Data on Atherosclerosis

June 23, 2014

By a News Reporter-Staff News Editor at Cardiovascular Week -- Data detailed on Cardiovascular Diseases and Conditions have been presented. According to news originating from Petah Tiqwa, Israel, by NewsRx correspondents, research stated, "In this study we report the use of gold nanorods (GNRs) as absorption contrast agents in the diffusion reflection (DR) method for the in vivo detection of atherosclerotic injury. The early detection and characterization of atherosclerotic vascular disease is considered to be one of the greatest medical challenges today."

Our news journalists obtained a quote from the research from Rabin Medical Center, "We show that macrophage cells, which are major components of unstable active atherosclerotic plaques, uptake gold nanoparticles, resulting in a change in the optical properties of tissue-like phantoms and a unique DR profile. In vivo DR measurements of rats that underwent injury of the carotid artery showed a clear difference between the DR profiles of the injured compared with healthy arteries."

According to the news editors, the research concluded: "The results suggest that DR measurements following GNRs administration represent a potential novel method for the early detection of atherosclerotic vascular disease."

For more information on this research see: Gold Nanorods as Absorption Contrast Agents for the Noninvasive Detection of Arterial Vascular Disorders Based on Diffusion Reflection Measurements. Nano Letters, 2014;14(5):2681-2687. Nano Letters can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society -; Nano Letters -

The news correspondents report that additional information may be obtained from R. Ankri, Rabin Med Center, Dept. of Cardiol, Petah Tiqwa, Israel. Additional authors for this research include D. Leshem-Lev, D. Fixler, R. Popovtzer, M. Motiei, R. Kornowski, E. Hochhauser and E.I. Lev (see also Cardiovascular Diseases and Conditions).

Keywords for this news article include: Asia, Israel, Nanorod, Cardiology, Petah Tiqwa, Nanotechnology, Atherosclerosis, Emerging Technologies, Cardiovascular Diseases and Conditions

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Source: Cardiovascular Week

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