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Sources Sought Notice - Hardware and Software Upgrades to 9.4T Animal MRI Scanner

June 18, 2014

Notice Type: Sources Sought Notice

Posted Date: 17-JUN-14

Office Address: Department of Health and Human Services; National Institutes of Health; National Institute on Drug Abuse, Station Support/Simplified Acquisitions; 31 Center DriveRoom 1B59 Bethesda MD 20892

Subject: Hardware and Software Upgrades to 9.4T Animal MRI Scanner

Classification Code: 66 - Instruments & laboratory equipment

Solicitation Number: HHS-NIH-NIDA-SSSA-SBSS-14-325

Contact: Lauren M. Phelps, Contract Specialist, Phone 3015942490, Email

Setaside: N/AN/A

Place of Performance (address): Baltimore , MD

Place of Performance (zipcode): 21224

Place of Performance Country: US

Description: Department of Health and Human Services

National Institutes of Health

National Institute on Drug Abuse, Station Support/Simplified Acquisitions

Contracting Office Address: Department of Health and Human Services, National Institutes of Health, National Institute on Drug Abuse, Station Support Simplified Acquisitions, 31 Center Drive, Room 1B59, Bethesda, MD 20892, UNITED STATES. Introduction: This is a Small Business Sources Sought notice. This is NOT a solicitation for proposals, proposal abstracts, or quotations. The purpose of this notice is to obtain information regarding: (1) the availability and capability of qualified small business sources, (2) whether they are small businesses; HUBZone small businesses, service-disabled, veteran-owned small businesses; 8(a) small businesses; veteran-owned small businesses; woman-owned small businesses; or small disadvantaged businesses; and (3) their size classification relative to the North American Industry Classification System (NAICS) code for the proposed acquisition. Your responses to the information requested will assist the Government in determining the appropriate acquisition method, including whether a set-aside is possible. Purpose and Objectives for the Procurement: The purpose of this potential requirement is acquisition of hardware and software upgrades in support of a Bruker BioSpin 9.4T Animal MRI Scanner (Serial No. BT000503) owned by the National Institute on Drug Abuse (NIDA) Intramural Research Program (IRP). Project Requirements: The Contractor must be able to provide the following hardware and software upgrades for a Bruker BioSpin 9.4T Animal MRI Scanner (Serial No. BT000503): 1) AVANCE III Console Upgrade a) Multiple RF Transmitter Channels i) Avance III RF/Data cabinet with electronics including two RF transmitter channels for MR signal excitation or hetero-nuclear experiments. Every transmit channel shall be controlled completely independently from the other. The electronics upgrade must include two digital RF signal generation units with fully digital frequency and waveform control b) RF Receiver Channel i) One RF receiver channel for MRI signal detection including broadband receiver (1H, X) with integrated AD converter, digital filter, expandable for parallel receiver configuration, HPPR/2 preamplifier c) Automatic Hardware Recognition i) The MR instrument must be equipped with an automatic hardware recognition system for basic system components such as amplifiers, gradient/shims, and RF coils. The plug recognition system provides automatic execution of set up and adjustment procedures under computer control d) Trigger Channel i) Real time input and output channels for the user control of external devices or triggered data acquisition by external sources, e.g. respiration or ECG. The trigger channel must have four output lines and two input lines e) RF Amplifier Interface Module i) The RF amplifier interface module must support connection of two RF amplifiers. f) Workstation i) The MR instrument shall be controlled by ParaVision on a Linux workstation. The MR workstation shall have 4GB RAM and a 500GB hard Disk as well as a PC mouse and keyboard and a 24 inch color flat panel monitor g) Gradient Amplifer Cabinet i) A gradient amplifier cabinet shall be set up including a basic cabinet including housing, line distribution, and wiring, a gradient and shim control unit, and a gradient and shim interface. The NIDA IRP has a gradient power supply, 3 gradient modules for X, y, and Z gradients, and a shim amplifier which may be reused as part of the amplifier cabinet requirement. h) Upgrade to ParaVision 6: Acquisition Workplace Including Computer i) The existing licenses of ParaVision acquisition workplace shall be upgraded to corresponding ParaVision 6.0 licenses, including a new and preconfigured computer and monitor. The computer hardware must include 64 bit Linux multicore workstation, 16 GB RAM, 1TB hard disk, and a full HD monitor, keyboard, and mouse. The software must include upgrade of all existing Para Vision and TopSpin licenses to corresponding ParaVision 6 software features and its application packages. i) Magnet Interface Panel (CCM Lite) i) The panel shall define interface connections for gradient and shim coil as well as RF coils. The panel shall be attached to the rear of the magnet. 4 RF coil sockets with automatic RF coil detection shall be included, as well as quick swap gradient/shim power connectors with automatic gradient/shim coil detection. j) RF Quadrature Combiner i) Active quadrature combiner for a maximal input power of 1kW k) RF Tune/Match Adapter i) The tune and match adapter shall provide tune and match capabilities for circularly polarized MRI coils without integrated preamplifier l) External Cable Set: Electronic Cabinet to RF Filter Plate or Faraday Enclosure i) Shall cover the external cabling between the electronic cabinet and Faraday enclosure attached to the rear of the magnet for installations without Faraday cage. In case of an installation with a Faraday cage, the cable shall extend from the electronic cabinets to the filter plate. The following is required: MT0320: 06m cable length, MT0321 10m cable length, MT0322 14m cable length, MT0323: 18m cable length. m) RF Filter Plate i) RF filter plate for already existing Faraday cage. The cable length shall be defined between the filter plate and aFaraday enclosure n) RF Interface Adapter i) The adapter shall support the following socket types: N-type connector for 1H, X high power transmit/receive coils, TWINAX connector providing the pin diode voltage for active coil decoupling, BNC type connector for 1H, X low power transmit/receive coils, 14 pin DIN-type connector for receive only surface coils, 4 RF pin/14 DC pin connector for 4 channel receive-only array coils. o) 60Hz Power Frequency p) Documentation and Installation of components q) 1H/19F Rat Head/Mouse Body Volume Coil - 40 mm i) Double resonant volume MRI RF coil designed for X nuclei investigation of the head of a rat or for investigations of the mouse body. Shall be designed for use in BGA-9S or bigger gradient sets. 1H linearly polarized, 19F linearly polarized, transmit/receive capabilities, outer/inner diameter for 75mm/40mm. The MRI RF coil must fit the following animal cradles: rat head, 40 m and Mouse Body, 40 mm. 2) Ancillary Upgrade for Biospec System BT000503 a) Parallel Receiver Upgrade (I): 1 to 4 Channels i) A fully equipped parallel proton-receiver configuration shall allow the application of 1H parallel imaging methods. The upgrade must include three additional 1H -only receiver channels for a total of 4 channels and ParaVision parallel imaging package for GRAPPA based image reconstruction b) Shim Amplifier i) The shim amplifier must have 8 channels and accept a maximum current of 5A c) Gradient/Shim Insert BGA-12S HP i) Gradient/shim inserts shall allow the optimization of the gradient/shim performance for smaller sample sizes and provide a higher level of spatial resolution. The inserts shall be designed to be quickly mounted inside the main system gradient and shim set. As soon as a gradient/shim insert is connected to the instrument, all protocol imaging and safety parameters shall be updated automatically. The insert must include actively shielded gradient and shim set BGA-12S-HP. d) Gradient/Shim Cooling DLHE i) Shall provide cooling for high duty cycle gradients and Cryohech. e) Transmit/Receive Volume Coil for Mice and Rates - 86 mm i) This volume coil shall be optimized for cross coil setups, i.e. for use as a transmit RF coil in combination with receive-only surface coils and arrays. The coil must also be able to be used as a receive volume coil. Must be capable of examining small rodents up to 650 g body weight. Shall be designed for use in B-GA12S or bigger gradient coils. 1H transmit and receive capabilities with active coil detuning, circularly polarized, outer/inner diameter 112 mm/86 mm f) Mouse Brain Surface Coil i) Anatomically shaped mouse brain surface coil: 1H circularly polarized, receive-only capabilities. g) Mouse Brain Array Coil i) Anatomically shaped 4 element mouse brain array coil: 1H 2x2 coil element topology with receive only capabilities h) Rat Brain Array Coil i) Anatomically shaped 4 element rat brain surface coil with 1H 2x2 coil element topology, receive only capabilities i) Low Noise Preamplifier for Planar Surface Coils i) The preamplifier is to be mounted on a split cradle and shall be designed for use in B-GA9S or bigger gradient coils. j) Mutli-Purpose Planar Surface Coil - 10 mm i) 1H receive-only surface coil with 1H receive only capabilities with active coil detuning, single loop coil with flexible cable, diameter 10 mm, pre-tuned/pre-matched. k) MultiPurpose Planar Surface Coil - 20 mm i) 1H receive-only surface coil with 1H receive only capabilities with active coil detuning, single loop coil with flexible cable, diameter 10 mm, pre-tuned/pre-matched. l) Cradle Base for Mouse Application Tips i) Basic cradle unit for mouse applications, to be combined with cradle tips. The base must include water hoses for body temperature control m) Mouse Tip for Surface Coil Applications n) Cradle Base for Rat Application Tips o) Rat Tip for Surface Coil and Body Applications p) Autopac Adapter for Existing Slider Table q) ParaVision Susceptibility Weighted Imaging Package i) The magnitude and phase data shall be combined to produce an enhanced contrast magnitude image which is sensitive to venous blood, hemorrhage and iron storage. r) ParaVision Spiral Imaging Pacakage i) Non-Cartesian acquisition for EPI based sequences

Anticipated Period of Performance: It is expected that delivery will be completed within 10 months after receipt of order. A firm fixed price contract is contemplated. Capability Statement: Contractors that believe they possess the ability to provide the required equipment and service should submit documentation of their ability to meet each of the project requirements to the Contract Specialist. Contractors must provide their Company Name, DUNS number, Physical Address, and Point of contact Information. Interested organizations are required to identify their type of business, applicable North American Industry Classification System Code, and size standards in accordance with the Small Business Administration. The government requests that no proprietary or confidential business data be submitted in a response to this notice. However, responses that indicate the information therein is proprietary will be properly safeguarded for Government use only. Capability statements must include the name and telephone number of a point of contact having authority and knowledge to discuss responses with Government representatives. Capability statements in response to this market survey that do not provide sufficient information for evaluation will be considered non-responsive. When submitting this information, please reference the solicitation notice number. All capability statements sent in response to this Sources Sought Notice must be submitted electronically (via email) to Lauren Phelps, Contract Specialist, at in MS Word format by or before the closing date of this announcement. All responses must be received by the specified due date and time in order to be considered. Note: This notice does not obligate the Government to award a contract or otherwise pay for the information provided in the response. No proprietary, classified, confidential, or sensitive information should be included in your response. The Government reserves the right to use information provided by respondents for any purpose deemed necessary and legally appropriate. Any organization responding to this notice should ensure that its response is complete and sufficiently detailed to allow the Government to determine the organization's qualifications to perform the work. Respondents are advised that the Government is under no obligation to acknowledge receipt of the information received or provide feedback to respondents with respect to any information submitted. After review of the responses received, pre-solicitation and solicitation notices may be published in Federal Business Opportunities. However, responses to this notice will not be considered adequate responses to a solicitation. The solicitation release date is pending. The Government intends to negotiate a fixed-price purchase order.


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