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Researchers at Allegheny General Hospital Have Reported New Data on Nephrology

June 23, 2014

By a News Reporter-Staff News Editor at Clinical Oncology Week -- Current study results on Nephrology have been published. According to news reporting originating in Pittsburgh, Pennsylvania, by NewsRx journalists, research stated, "Raman molecular imaging was evaluated as a tool for differentiating between kidney tumors which are sometimes confused using conventional histopathological methods. Renal oncocytoma and chromophobe renal cell carcinoma are two kidney tumors which occasionally possess overlapping histological features."

The news reporters obtained a quote from the research from Allegheny General Hospital, "There is no reliable alternative method to routine histologic examination for differentiating these neoplasms. However, a conclusive diagnosis is important, as renal oncocytoma is benign and chromophobe renal cell carcinoma has malignant potential, requiring different treatment options. In an investigation based on 88 patients, a partial least squares discriminant analysis model generated from Raman molecular images distinguished between chromophobe renal cell carcinoma and renal oncocytoma with a performance of 86% sensitivity and 81% specificity."

According to the news reporters, the research concluded: "These initial observations suggest that Raman molecular imaging may be applied not only to the differentiation of these kidney tumors but also to other applications for which conventional histological methods are not sufficient for a conclusive diagnosis."

For more information on this research see: Distinguishing between renal oncocytoma and chromophobe renal cell carcinoma using Raman molecular imaging. Journal of Raman Spectroscopy, 2014;45(4):274-280. Journal of Raman Spectroscopy can be contacted at: Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ, USA. (Wiley-Blackwell -; Journal of Raman Spectroscopy -

Our news correspondents report that additional information may be obtained by contacting S. Stewart, Allegheny Gen Hosp, Div Urol, Pittsburgh, PA 15212, United States. Additional authors for this research include H. Kirschner, P.J. Treado, R. Priore, M. Tretiakova and J.K. Cohen (see also Nephrology).

Keywords for this news article include: Kidney, Oncology, Carcinoma, Pittsburgh, Nephrology, Pennsylvania, United States, Nanotechnology, Molecular Imaging, Emerging Technologies, North and Central America

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Source: Clinical Oncology Week

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