The news reporters obtained a quote from the research, "We reviewed the literature on possible mechanisms for PSP94 protection for prostate cancer. One possible mechanism is tumor suppression, as PSP94 has been observed to inhibit cell or tumor growth in in vitro and in vivo models. Another novel mechanism, which we propose in this review article, is that PSP94 may protect against prostate cancer by preventing or limiting an intracellular fungal infection in the prostate. This mechanism is based on the recent discovery of PSP94's fungicidal activity in low-calcium environments (such as the cytosol of epithelial cells), and accumulating evidence suggesting a role for inflammation in prostate carcinogenesis. We provide further details of our proposed mechanism in this review article."
According to the news reporters, the research concluded: "To explore this mechanism, future studies should consider screening prostate specimens for fungi using the rapidly expanding number of molecular techniques capable of identifying infectious agents from the entire tree of life. Prostate 74:569-578, 2014."
For more information on this research see: MSMB Variation and Prostate Cancer Risk: Clues Towards a Possible Fungal Etiology. Prostate, 2014;74(6):569-578. Prostate can be contacted at: Wiley-Blackwell,
Our news correspondents report that additional information may be obtained by contacting S. Sutcliffe,
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Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC
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