News Column

New Findings on LactoBacillus rhamnosus Discussed by Researchers at Center for Biotechnology

June 24, 2014



By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators discuss new findings in Gram-Positive Bacteria. According to news reporting from Gurgaon, India, by NewsRx journalists, research stated, "Lactobacillus rhamnosus GG, a widely used Gram-positive probiotic strain, is clinically well known for its perceived health-promoting effects. It has recently been shown to display proteinaceous pilus fibres (called SpaCBA) on its cell surface."

The news correspondents obtained a quote from the research from Center for Biotechnology, "Structurally, SpaCBA pili possess a characteristic three-pilin polymerized architecture, with repeating SpaA major pilins that form the backbone and two types of minor subunits (SpaB and SpaC). In this study, recombinant SpaA protein was purified, characterized and crystallized."

According to the news reporters, the research concluded: "The crystals diffracted to a resolution of 2.0?A and belonged to space group C2, with unit-cell parameters a=227."

For more information on this research see: Purification, crystallization and preliminary crystallographic analysis of the SpaA backbone-pilin subunit from probiotic Lactobacillus rhamnosus GG. Acta Crystallographica Section F, Structural Biology and Crystallization Communications, 2013;69(Pt 10):1182-5. Acta Crystallographica Section F, Structural Biology and Crystallization Communications can be contacted at: Blackwell Publishing Inc, 350 Main St, Malden, MA 02148, USA (see also Gram-Positive Bacteria).

Our news journalists report that additional information may be obtained by contacting D. Singh, Regional Centre for Biotechnology, 180 Udyog Vihar Phase 1, Gurgaon, Haryana 122 016, India. Additional authors for this research include I. von Ossowski, A. Palva and V. Krishnan.

Publisher contact information for the journal Acta Crystallographica Section F, Structural Biology and Crystallization Communications is: Blackwell Publishing Inc, 350 Main St, Malden, MA 02148, USA.

Keywords for this news article include: Asia, India, Gurgaon, Lactobacillales, Lactobacillaceae, Gram Positive Rods, Gram Positive Bacteria, Gram-Positive Bacteria, Lactobacillus rhamnosus, Gram Positive Asporogenous Rods.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


For more stories covering the world of technology, please see HispanicBusiness' Tech Channel



Source: Life Science Weekly