News Column

Findings on Fatigue Reported by Investigators at Shanghai Jiao-Tong University

June 27, 2014

By a News Reporter-Staff News Editor at Health & Medicine Week -- Researchers detail new data in Fatigue. According to news reporting out of Shanghai, People's Republic of China, by NewsRx editors, research stated, "Dense hydroxyapatite (HA) ceramic is a promising material for hard tissue repair due to its unique physical properties and biologic properties. However, the brittleness and low compressive strength of traditional HA ceramics limited their applications, because previous sintering methods produced HA ceramics with crystal sizes greater than nanometer range."

Our news journalists obtained a quote from the research from Shanghai Jiao-Tong University, "In this study, nano-sized HA powder was employed to fabricate dense nanocrystal HA ceramic by high pressure molding, and followed by a three-step sintering process. The phase composition, microstructure, crystal dimension and crystal shape of the sintered ceramic were examined by X-ray diffraction (XRD) and scanning electron microscopy (SEM). Mechanical properties of the HA ceramic were tested, and cytocompatibility was evaluated. The phase of the sintered ceramic was pure HA, and the crystal size was about 200 nm. The compressive strength and elastic modulus of the HA ceramic were comparable to human cortical bone, especially the good fatigue strength overcame brittleness of traditional sintered HA ceramics."

According to the news editors, the research concluded: "Cell attachment experiment also demonstrated that the ceramics had a good cytocompatibility."

For more information on this research see: Strength and fatigue properties of three-step sintered dense nanocrystal hydroxyapatite bioceramics. Frontiers of Materials Science, 2013;7(2):190-195. Frontiers of Materials Science can be contacted at: Higher Education Press, Shatanhou St 55, Beijing 100009, Peoples R China. (Springer -; Frontiers of Materials Science -

Our news journalists report that additional information may be obtained by contacting W.G. Guo, Shanghai Jiao Tong University, Sch Med, Renji Hosp, Dept. of Orthoped, Shanghai 200127, People's Republic of China. Additional authors for this research include Z.Y. Qiu, H. Cui, C.M. Wang, X.J. Zhang, I.S. Lee, Y.Q. Dong and F.Z. Cui (see also Fatigue).

Keywords for this news article include: Asia, Fatigue, Shanghai, Phosphates, Hydroxyapatites, Phosphoric Acids, People's Republic of China

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Source: Health & Medicine Week

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