News Column

Findings from University of Pittsburgh Broaden Understanding of Indicators and Reagents

June 27, 2014

By a News Reporter-Staff News Editor at Drug Week -- Researchers detail new data in Indicators and Reagents. According to news originating from Pittsburgh, Pennsylvania, by NewsRx correspondents, research stated, "The development of chelating agents for copper radionuclides in positron emission tomography radiopharmaceuticals has been a highly active and important area of study in recent years. The rapid evolution of chelators has resulted in highly specific copper chelators that can be readily conjugated to biomolecules and efficiently radiolabeled to form stable complexes in vivo."

Our news journalists obtained a quote from the research from the University of Pittsburgh, "Chelators are not only designed for conjugation to monovalent biomolecules but also for incorporation into multivalent targeting ligands such as theranostic nanoparticles. These advancements have strengthened the role of copper radionuclides in the fields of nuclear medicine and molecular imaging."

According to the news editors, the research concluded: "This review emphasizes developments of new copper chelators that have most greatly advanced the field of copper-based radiopharmaceuticals over the past 5years."

For more information on this research see: Chelators for copper radionuclides in positron emission tomography radiopharmaceuticals. Journal of Labelled Compounds & Radiopharmaceuticals, 2014;57(4):224-230. Journal of Labelled Compounds & Radiopharmaceuticals can be contacted at: Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ, USA. (Wiley-Blackwell -; Journal of Labelled Compounds & Radiopharmaceuticals -

The news correspondents report that additional information may be obtained from Z.X. Cai, University of Pittsburgh, Dept. of Radiol, Pittsburgh, PA 15219, United States (see also Indicators and Reagents).

Keywords for this news article include: Pittsburgh, Pennsylvania, United States, Radiopharmaceuticals, Indicators and Reagents, North and Central America

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Source: Drug Week

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