By a News Reporter-Staff News Editor at Cancer Gene Therapy Week -- Investigators publish new report on Biotechnology. According to news reporting originating from Shenzhen, People's Republic of China, by NewsRx correspondents, research stated, "Folic acid (FA)-targeted indocyanine green (ICG)-loaded nanoparticles (NPs) (FA-INPs) were developed to a near-infrared (NIR) fluorescence theranostic nanoprobe for targeted imaging and photothermal therapy of cancer. The FA-INPs with good monodispersity exhibited excellent size and fluorescence stability, preferable temperature response under laser irradiation, and specific molecular targeting to MCF-7 cells with FA receptor overexpression, compared to free ICG."
Our news editors obtained a quote from the research from the Shenzhen Institutes of Advanced Technology, "The FA-INPs enabled fluorescence imaging to in situ monitor the tumor accumulation of the ICG. The cell survival rate assays in vitro and photothermal therapy treatments in vivo indicated that FA-INPs could efficiently targeted and suppressed MCF-7 cells and xenograft tumors."
According to the news editors, the research concluded: "Hence, the FA-INPs are notable theranostic NPs for imaging-guided cancer therapy in clinical application."
For more information on this research see: Robust ICG Theranostic Nanoparticles for Folate Targeted Cancer Imaging and Highly Effective Photothermal Therapy. ACS Applied Materials & Interfaces, 2014;6(9):6709-6716. ACS Applied Materials & Interfaces can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; ACS Applied Materials & Interfaces - www.pubs.acs.org/journal/aamick)
The news editors report that additional information may be obtained by contacting M.B. Zheng, Chinese Academy Sci, Shenzhen Inst Adv Technol, Inst Biomed & Biotechnol, Guangdong Key Lab NanomedShenzhen Key Lab Canc N, Shenzhen 518055, People's Republic of China. Additional authors for this research include P.F. Zhao, Z.Y. Luo, P. Gong, C.F. Zheng, P.F. Zhang, C.X. Yue, D.Y. Gao, Y.F. Ma and L.T. Cai (see also Biotechnology).
Keywords for this news article include: Asia, Biotechnology, Shenzhen, Oncology, Nanoparticle, Nanotechnology, Cancer Gene Therapy, Emerging Technologies, People's Republic of China
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