ENP Newswire -
Release date- 13062014 -
This technology was originally of interest to
Benefits for the existing personal care market include being able to make preservative free product, an increase in shelf life, and a 98% reduction in shipping weights and associated greenhouse gasses by removing the water.
A dry formulation would also allow
During the scale up work,
As a result of the success with the
MIT Impregnation Study
The first target molecule was CoQ Enzyme 10, a well known health ingredient. The study was a success and proved that beta glucan could be well impregnated. While the work has not included any molecular characterization or efficacy testing yet, this study demonstrated the tremendous platform potential of the PGX technology to allow
With respect to beta glucan specifically, we can now look at expanding the use of beta glucan as a delivery system for topical applications given the demonstrated properties of beta glucan to deeply penetrate the skin down to the derm level. Also, upon completion of bioavaialability studies, oral combination of active ingredients impreganted with beta glucan will be considered for time release applications. While this work is still early stage, the technical success is an essential first step to ensure we can make a product.
With that in mind, further scientific and efficacy studies will be conducted. 'The results of this first impregnation study with this enabling technology is very exciting and opens up many opportunities to develop new products and superior formulations for the pharmaceutical and nutraceutical sectors, in line with our stated goals', said
Other Drying Tests
During 2014, the PGX platform was tested on other compounds to see how the resulting products would work with the technology. The primary intent of this test was to establish the broad application potential of PGX to effectively dry challenging biopolymers and allow for particle morphologies that offered the potential of enhanced performance. Two tests were conducted at
The first one was conducted on chitosan, a well known compound used for wound healing that is most commonly extracted from shellfish. The second test was conducted on nano-crystalline cellulose (CNC), a product which is the focus of much research and development by the forest industry.
This CNC product has some tremendous properties but faces drying challenges using current technologies that limits the functionality of the dried product. The ability of PGX to make a nano-particle aerogel product, something not possible with traditional spray drying, may allow for this product to be commercialized with its full potential.
In summary, the ability of PGX to potentially work and add value for other industries who face drying challenges with their biopolymers and biomaterials allows for
It is anticipated that several of these meetings will lead to mutually beneficial business opportunities for
Because of the huge potential that PGX represents to
'We have a new manufacturing facility coming on stream, sales forecasts suggesting record volumes, increased awareness of our flagship avenanthramides products, and now the tremendous promise of PGX. This is an exciting time for
About the Technology
This Technology was invented by Dr. Temelli from the
The technology is called 'PGX Technology', a novel spray drying technique for processing water- soluble biopolymers, including oat beta glucan, utilizing the unique and tuneable properties of
PGX Technology is a platform that can produce numerous morphologies of biopolymers ranging from fine fibres to granular powder, which are highly water soluble and could find commercial success in a wide range of industries including functional foods, nutraceuticals, cosmeceuticals, and pharmaceutical products. This technology operates at lower temperatures than conventional spray drying allowing incorporation of thermosensitive bioactives as well.
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