Science & Technology Desk
Iranian researchers at
"We electrospun cellulose acetate/gelatin membranes in various compositions and evaluated their performance as a scaffold for skin tissue engineering and wound dressing," she said.
The expert noted that tissue-engineered scaffolds and wound dressings should be hydrophilic to allow oxygen and fluid exchange, and absorb excess exudates.
Vatankhah explained that a wound dressing should be easily removed without causing tissue damage and a tissue-engineered scaffold should be able to adhere to the wound and support cell proliferation during skin regeneration.
"We changed the composition of cellulose acetate and gelatin in composite cellulose acetate/gelatin scaffolds and found that increasing the amount of gelatin will increase the adhesion properties of the nanofiber," she said.
Electrospun cellulose acetate/gelatin (25/75) nanofibers can be a potential tissue-engineered scaffold and the 75/25 can be a potential low-adherent wound dressing.
Electrospinning uses an electrical charge to draw very fine (typically on the micro or nano scale) fibers from a liquid.
Dermal fibroblasts are cells within the dermis layer of skin, which are responsible for generating connective tissue and allowing the skin to recover from injury.
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