•In just a short time, the DEINOCHEM program has obtained highly promising results in the effective production of several key molecules.•This performance is the result of the successful combination of
In their own laboratory,
These results enable
These bioproducts obtained with the Deinococcus bacteria are high-added-value industrial compounds, providing applications in cosmetics and food industry. Others can be used in the fragrance industry and in other everyday products, such as detergents, home and personal care products. To date, these molecules have mainly been derived from oil or plant extracts, with low yield and high production cost.
This progress constitutes a major proof of concept, opening the way for the production of many chemical intermediates and speciality molecules. This represents a potential of several hundred million euros in turnover. Some of these compounds can be sold for up to
"With this exclusive license, we have significantly consolidated the progress made in the DEINOCHEM program, on which we continue to focus our efforts," said
Jean-FranÇois Rous, Chairman of GENOPLANTE-VALOR, said, "This licensing agreement is a real opportunity to industrially showcase the excellence of French academic research and to forge contacts with a French SME whose technology is highly promising and can be rapidly produced industrially. It also demonstrates the potential for promoting work carried out in the plant biotechnology context in other fields such as industrial biotechnologies."
The DEINOCHEM program
The DEINOCHEM program aims to develop and market high performance and cost-effective production processes for bio-sourced molecules originating from biomass and based on the exploitation of Deinococcus bacteria. The compounds produced by these bacteria will be able to replace current compounds, which are traditionally petro-sourced. DEINOCHEM's priority target is isoprenoids, which are one of the most diverse families of natural substances (over 22,000 isoprenoid compounds listed to date). They are used in many industrial applications, as they are found in cosmetics, perfumes, home and personal care products, as well as food and feed. Deinococcus bacteria are naturally endowed with capacities that make them ideal for this type of development - the natural expression of some isoprenoids, resistance to toxicity, adaptation to high-speed metabolic engineering, etc. DEINOCHEM, for which the investment is estimated at €15.9 million by 2018, will receive over 3.5 years €5.9 million as financial support from ADEME and CGI in the context of the "Investissements d'Avenir" (Investments for the Future) program.
The patent covered by the licensing agreement concerns a key enzyme, DXS, involved in the isoprenoid biosynthesis pathway and whose optimization facilitates the hyperproduction of isoprenoids by bacteria and plants. This patent was filed by GENOPLANTE-VALOR and is the product of an ANR research program labelled Genoplante. This patent's promotion was entrusted to INRA TRANSFERT, the INRA subsidiary responsible for valorizing innovations. GENOPLANTE-VALOR is a company involved in the
More information at www.gisbiotechnologiesvertes.com
GENOPLANTE-VALOR Edwige Pilard
Tel.: + 33 (0) 1 42 75 95 86
INRA Transfert, a INRA subsidiary, is a project management consulting company specialized in the field of innovative technologies arising from INRA research laboratories. INRA Transfert's team manages the technology portfolio of INRA and GENOPLANTE-VALOR through operating agreements with industrialists and supports the development of innovative young companies.
More information at www.inra-transfert.fr
More information at www.deinove.com
Tel.: +33 (0) 4 48 19 01 28
Communication, Marketing and IR Manager
Tel.: +33 (0) 4 48 19 01 60
ALIZE RP, Press relations Caroline Carmagnol
Tel.: +33 (0) 1 70 22 53 90
Mobile: +33 (0) 6 64 18 99 59
DEINOCHEM: a promising start notably due to work carried out at INRA http://hugin.info/142979/R/1793155/617320.pdf
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