News Column

Studies from University of Malaya Further Understanding of Amino Acids

June 17, 2014

By a News Reporter-Staff News Editor at Journal of Technology -- Fresh data on Amino Acids are presented in a new report. According to news reporting from Kuala Lumpur, Malaysia, by VerticalNews journalists, research stated, "Two microbial isolates from a Malaysian shoreline were found to be capable of degrading N-acylhomoserine lactones. Both Matrix Assisted Laser Desorption Ionization-Time of Flight-Mass Spectrometry and 18S rDNA phylogenetic analyses confirmed that these isolates are Rhodotorula mucilaginosa."

The news correspondents obtained a quote from the research from the University of Malaya, "Quorum quenching activities were detected by a series of bioassays and rapid resolution liquid chromatography analysis. The isolates were able to degrade various quorum sensing molecules namely N-hexanoyl-L-homoserine lactone (C6-HSL), N-(3-oxo-hexanoyl)-L-homoserine lactone (3-oxo-C6-HSL) and N-(3-hydroxyhexanoyl)-L-homoserine lactone (3-hydroxy-C6-HSL). Using a relactonisation assay to verify the quorum quenching mechanism, it is confirmed that Rh. mucilaginosa degrades the quorum sensing molecules via lactonase activity."

According to the news reporters, the research concluded: "To the best of our knowledge, this is the first documentation of the fact that Rh. mucilaginosa has activity against a broad range of AHLs namely C6-HSL, 3-oxo-C6-HSL and 3-hydroxy-C6-HSL."

For more information on this research see: Rhodotorula mucilaginosa, a quorum quenching yeast exhibiting lactonase activity isolated from a tropical shoreline. Sensors, 2014;14(4):6463-73. (Elsevier -; Sensors -

Our news journalists report that additional information may be obtained by contacting N.A. Ghani, Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia. Additional authors for this research include J. Sulaiman, Z. Ismail, X.Y. Chan, W.F. Yin and K.G Chan.

Keywords for this news article include: Asia, Malaysia, Homoserine, Amino Acids, Kuala Lumpur.

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Source: Journal of Technology

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