News Column

Reports by D. Huo and Co-Researchers Describe Recent Advances in Colloids and Interface Science

June 17, 2014



By a News Reporter-Staff News Editor at Journal of Technology -- A new study on Colloids and Interface Science is now available. According to news reporting originating from Jiangsu, People's Republic of China, by VerticalNews correspondents, research stated, "Au@Ag core-shell nanoparticles (NPs) integrating both antibacterial and X-ray attenuation capabilities were facilely synthesized in aqueous solution. These NPs modified with methoxy-PEG-SH (m-PEG) on the surface rendered them favorable dispersity and stability in water, resulting in enhancement of their blood circulation time."

Our news editors obtained a quote from the research, "X-ray photoelectron spectroscope (XPS) and high-resolution transmission electron microscope (HRTEM) results confirmed the core-shell structure of m-PEG-Au@Ag NPs. The m-PEG-Au@Ag NPs showed low cytotoxicity and strong X-ray absorption potency in vitro. Further in vivo study showed that as-synthesized NPs offered a pronounced contrast and prolonged their circulation time in the blood stream with negligible toxic effect in vivo. Besides, m-PEG-Au@Ag NPs had significant bacteriostatic effect toward common bacteria like Escherichia coli and Staphylococcus aureus as demonstrated by broth dilution assay."

According to the news editors, the research concluded: "Given their low-cytotoxicity and high CT attenuation efficacy, m-PEG-Au@Ag NPs had a promising potential for use as CT enhancing and antibacterial agents."

For more information on this research see: Fabrication of Au@Ag core-shell NPs as enhanced CT contrast agents with broad antibacterial properties. Colloids and Surfaces B-Biointerfaces, 2014;117():29-35. Colloids and Surfaces B-Biointerfaces can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands.

The news editors report that additional information may be obtained by contacting D. Huo, Jiangsu Entry Exit Inspect & Quarantine Bur, Wuxi 210001, Jiangsu, People's Republic of China. Additional authors for this research include J. He, H. Li, H.P. Yu, T.T. Shi, Y.H. Feng, Z.Y. Zhou and Y. Hu.

Keywords for this news article include: Asia, Jiangsu, People's Republic of China, Colloids and Interface Science

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Journal of Technology


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