News Column

Data on Molecular Diagnostics Reported by Researchers at Genentech, Inc.

June 20, 2014

By a News Reporter-Staff News Editor at Science Letter -- Investigators publish new report on Molecular Diagnostics. According to news originating from South San Francisco, California, by NewsRx correspondents, research stated, "Extracellular vesicles (EVs), including exosomes and microvesicles, have been shown to carry a variety of biomacromolecules including mRNA, microRNA and other non-coding RNAs. Within the past 5 years, EVs have emerged as a promising minimally invasive novel source of material for molecular diagnostics."

Our news journalists obtained a quote from the research from Genentech, Inc., "Although EVs can be easily identified and collected from biological fluids, further research and proper validation is needed in order for them to be useful in the clinical setting. In addition, innovative and more efficient means of nucleic acid profiling are needed to facilitate investigations into the cellular and molecular mechanisms of EV function and to establish their potential as useful clinical biomarkers and therapeutic tools."

According to the news editors, the research concluded: "In this article, we provide an overview of recent technological improvements in both upstream EV isolation and downstream analytical technologies, including digital PCR and next generation sequencing, highlighting future prospects for EV-based molecular diagnostics."

For more information on this research see: Emerging technologies in extracellular vesicle-based molecular diagnostics. Expert Review of Molecular Diagnostics, 2014;14(3):307-21 (see also Molecular Diagnostics).

The news correspondents report that additional information may be obtained from S. Jia, Oncology Biomarker Development, Genentech Inc, South San Francisco, CA 94080, United States. Additional authors for this research include D. Zocco, M.L. Samuels, M.F. Chou, R. Chammas, J. Skog, N. Zarovni, F. Momen-Heravi and W.P Kuo.

Keywords for this news article include: California, Technology, United States, South San Francisco, Molecular Diagnostics, North and Central America.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Science Letter

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