News Column

Study Results from Chulalongkorn University Update Understanding of Peptides and Proteins

June 17, 2014

By a News Reporter-Staff News Editor at Life Science Weekly -- Current study results on Proteins have been published. According to news reporting from Bangkok, Thailand, by NewsRx journalists, research stated, "In this study, a 'green chemistry' approach was introduced to synthesize silk sericin (SS)-capped silver nanoparticles (AgNPs) under an alkaline condition (pH 11) using SS as a reducing and stabilizing agent instead of toxic chemicals. The SS-capped AgNPs were successfully synthesized at various concentrations of SS and AgNO3, but the yields were different."

The news correspondents obtained a quote from the research from Chulalongkorn University, "A higher yield of SS- capped AgNPs was obtained when the concentrations of SS and AgNO3 were increased. The SS- capped AgNPs showed a round shape and uniform size with diameter at around 48 to 117 nm. The Fourier transform infrared (FT-IR) spectroscopy result proved that the carboxylate groups obtained from alkaline degradation of SS would be a reducing agent for the generation of AgNPs while COO- and NH2+ groups stabilized the AgNPs and prevented their precipitation or aggregation. Furthermore, the SS-capped AgNPs showed potent anti-bacterial activity against various gram-positive bacteria (minimal inhibitory concentration (MIC) 0.008 mM) and gram-negative bacteria (MIC ranging from 0.001 to 0.004 mM)."

According to the news reporters, the research concluded: "Therefore, the SS-capped AgNPs would be a safe candidate for anti-bacterial applications."

For more information on this research see: Green synthesis of silk sericin-capped silver nanoparticles and their potent anti-bacterial activity. Nanoscale Research Letters, 2014;9():9-15. Nanoscale Research Letters can be contacted at: Springer, 233 Spring St, New York, NY 10013, USA. (Springer -; Nanoscale Research Letters -

Our news journalists report that additional information may be obtained by contacting P. Aramwit, Chulalongkorn University, Fac Sci, Dept. of Chem, Sensor Res Unit, Bangkok 10330, Thailand. Additional authors for this research include N. Bang, J. Ratanavaraporn and S. Ekgasit (see also Proteins).

Keywords for this news article include: Asia, Bangkok, Thailand, Proteins, Nanoparticle, Nanotechnology, Emerging Technologies

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Life Science Weekly

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