By a News Reporter-Staff News Editor at Life Science Weekly -- Research findings on Genetic Engineering are discussed in a new report. According to news reporting originating in Beijing, People's Republic of China, by NewsRx journalists, research stated, "In assessing an insect-resistant genetically engineered (IRGE) crop before its commercialization, researchers normally use so-called 'Tier-1 assays' as the initial step to determine the effects of the crop on non-target organisms. In these tests, the insecticidal proteins (IPs) produced by the IRGEs are added to the diets of test organisms in the laboratory."
The news reporters obtained a quote from the research from the Institute of Plant Protection, "Test organisms in such assays can be directly exposed to much higher concentrations of the test IPs than they would encounter in the field. The results of Tier-1 assays are thus more conservative than those generated in studies in which the organisms are exposed to the IPs by feeding on IRGE plant tissue or in the case of predators or parasites, by feeding on invertebrate prey or hosts that have fed on IRGE plant tissue. In this report, we consider three important factors that must be considered in Tier-1 assays: (i) methods for delivery of the IP to the test organisms; (ii) the need for and selection of compounds used as positive controls; and (iii) methods for monitoring the concentration, stability and bioactivity of the IP during the assay. We also analyze the existing data from Tier-1 assays regarding the toxicity of Bt Cry proteins to non-target arthropod species."
According to the news reporters, the research concluded: "The data indicate that the widely used Bt proteins have no direct toxicity to non-target organisms."
For more information on this research see: Tier-1 assays for assessing the toxicity of insecticidal proteins produced by genetically engineered plants to non-target arthropods. Insect Science, 2014;21(2):125-34. Insect Science can be contacted at: Blackwell Publishing Inc, 350 Main St, Malden, MA 02148, USA. (Wiley-Blackwell - www.wiley.com/; Insect Science - onlinelibrary.wiley.com/journal/10.1111/(ISSN)1744-7917)
Our news correspondents report that additional information may be obtained by contacting Y.H. Li, State Key Laboratory for Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, People's Republic of China. Additional authors for this research include J. Romeis, K.M. Wu and Y.F Peng (see also Genetic Engineering).
The publisher of the journal Insect Science can be contacted at: Blackwell Publishing Inc, 350 Main St, Malden, MA 02148, USA.
Keywords for this news article include: Asia, Beijing, Peptides, Proteins, Technology, Amino Acids, Bioengineering, Genetic Engineering, People's Republic of China.
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