News Column

Researchers at Hong Kong Polytechnic University Target Bone Research

June 18, 2014

By a News Reporter-Staff News Editor at Biotech Week -- Current study results on Bone Research have been published. According to news reporting originating in Hong Kong, People's Republic of China, by NewsRx journalists, research stated, "With the development of micro-computed tomography (micro-CT) technology, it is possible to construct three-dimensional (3D) models of human bone without destruction of samples and predict mechanical behavior of bone using finite element analysis (FEA). However, due to large number of elements required for constructing the FE models of entire bone, this demands a substantial computational effort and the analysis usually needs a high level of computer."

The news reporters obtained a quote from the research from Hong Kong Polytechnic University, "In this article, a voxel-based approach for generation of FE models of entire bone with microscopic architecture from micro-CT image data is proposed. To enable the FE analyses of entire bone to be run even on a general personal computer, grayscale intensity thresholds were adopted to reduce the amount of elements. Human metacarpal bone (MCP) bone was used as an example for demonstrating the applicability of the proposed method. The micro-CT images of the MCP bone were combined and converted into 3D array of pixels. Dual grayscale intensity threshold parameters were used to distinguish the pixels of bone tissues from those of surrounding soft tissues and improve predictive accuracy for the FE analyses with different sizes of elements. The method of selecting an appropriate value of the second grayscale intensity threshold was also suggested to minimize the area error for the reconstructed cross-sections of a FE structure."

According to the news reporters, the research concluded: "Experimental results showed that the entire FE MCP bone with microscopic architecture could be modeled and analyzed on a personal computer with reasonable accuracy."

For more information on this research see: Voxel-based approach to generate entire human metacarpal bone with microscopic architecture for finite element analysis. Bio-medical Materials and Engineering, 2014;24(2):1469-84 (see also Bone Research).

Our news correspondents report that additional information may be obtained by contacting C.Y. Tang, Dept. of Industrial and Systems Engineering, The Hong Kong Polytechnic University, Hong Kong, People's Republic of China. Additional authors for this research include C.P. Tsui, Y.M. Tang, L. Wei, C.T. Wong, K.W. Lam, W.Y. Ip, W.W. Lu and M.Y Pang.

Keywords for this news article include: Asia, Hong Kong, Computers, Bone Research, People's Republic of China.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Biotech Week

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