News Column

Reports from Kagoshima University Provide New Insights into Oral Candidiasis

June 17, 2014

By a News Reporter-Staff News Editor at Life Science Weekly -- New research on Candida Infection is the subject of a report. According to news reporting from Kagoshima, Japan, by NewsRx journalists, research stated, "Although oral Candida easily adheres to denture base materials, many denture detergents are effective only against bacteria but not against Candida. Silver nanoparticles (AgNPs), which are known to have potent antibacterial and antifungal activity, have been used in the prevention of oral candidiasis (OC)."

The news correspondents obtained a quote from the research from Kagoshima University, "We evaluated the adherence of Candida albicans and Candida glabrata on a heat-cured Acron resin piece supported by AgNPs by low-vacuum scanning electron microscopy (SEM) and measuring colony-forming units. C. albicans and C. glabrata increasingly adhered to the resin surface of the control piece over time, but the adhesion AgNP of both Candida species to the AgNP-coated surface was significantly inhibited (P < 0.001). Low-vacuum SEM revealed that C. albicans and C. glabrata on the resin surface of control pieces appeared as oval colonies, with a major axis of 3-4 mu m and a smooth cell wall, but those on the AgNP-coated resin surface were less abundant than the control and showed swollen yeast features, with a major axis of more than 5 mu m and a corrugated cell wall."

According to the news reporters, the research concluded: "Our results suggest a way to prevent denture-associated OC by using denture base materials processed by AgNPs."

For more information on this research see: In Vitro Antifungal Activity against Oral Candida Species Using a Denture Base Coated with Silver Nanoparticles. Journal of Nanomaterials, 2014;():1-6. Journal of Nanomaterials can be contacted at: Hindawi Publishing Corporation, 410 Park Avenue, 15TH Floor, #287 Pmb, New York, NY 10022, USA. (Hindawi Publishing -; Journal of Nanomaterials -

Our news journalists report that additional information may be obtained by contacting Y. Kamikawa, Kagoshima University, Grad Sch Med & Dental Sci, Dept. of Maxillofacial Diagnost & Surg Sci, Kagoshima 8908544, Japan. Additional authors for this research include D. Hirabayashi, T. Nagayama, J. Fujisaki, T. Hamada, R. Sakamoto, Y. Kamikawa and K. Sugihara (see also Candida Infection).

Keywords for this news article include: Asia, Japan, Kagoshima, Nanoparticle, Nanotechnology, Oral Candidiasis, Candida Infection, Risk and Prevention, Emerging Technologies

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Life Science Weekly

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