By a News Reporter-Staff News Editor at Life Science Weekly -- New research on Nanotechnology is the subject of a report. According to news reporting from Victoria, Australia, by NewsRx journalists, research stated, "We report a versatile approach for the design of substrate-independent low-fouling surfaces via mussel-inspired immobilisation of zwitterionic peptides. Using mussel-inspired polydopamine (PDA) coatings, zwitterionic glutamic acid-and lysine-based peptides were immobilised on various substrates, including noble metals, metal oxides, polymers, and semiconductors."
The news correspondents obtained a quote from the research from the University of Melbourne, "The variation of surface chemistry and surface wettability upon surface treatment was monitored with X-ray photoelectron spectroscopy (XPS) and water contact angle measurements. Following peptide immobilisation, the surfaces became more hydrophilic due to the strong surface hydration compared with PDA-coated surfaces. The peptide-functionalised surfaces showed resistance to human blood serum adsorption and also effectively prevented the adhesion of gram-negative and gram-positive bacteria (i.e., Escherichia coli and Staphylococcus epidermidis) and mammalian cells (i.e., NIH 3T3 mouse embryonic fibroblast cells)."
According to the news reporters, the research concluded: "The versatility of mussel-inspired chemistry combined with the unique biological nature and tunability of peptides allows for the design of low-fouling surfaces, making this a promising coating technique for various applications."
For more information on this research see: Nanoscale engineering of low-fouling surfaces through polydopamine immobilisation of zwitterionic peptides. Soft Matter, 2014;10(15):2656-63. (Royal Society of Chemistry - www.rsc.org/; Soft Matter - pubs.rsc.org/en/journals/journalissues/sm)
Our news journalists report that additional information may be obtained by contacting J. Cui, Dept. of Chemical and Biomolecular Engineering, The University of Melbourne, Parkville, Victoria 3010, Australia. Additional authors for this research include Y. Ju, K. Liang, H. Ejima, S. Lorcher, K.T. Gause, J.J. Richardson and F. Caruso (see also Nanotechnology).
Keywords for this news article include: Victoria, Peptides, Proteins, Chemicals, Chemistry, Nanoscale, Amino Acids, Engineering, Nanotechnology, Emerging Technologies, Australia and New Zealand.
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