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Recent Findings from Osaka University Has Provided New Data on Bioscience and Bioengineering

June 17, 2014

By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators discuss new findings in Life Science Research. According to news reporting out of Osaka, Japan, by NewsRx editors, research stated, "A total of 412 strains belonging to 14 genera of clavicipitoid entomopathogenic fungi (EPF) were screened for activities against two economically important plant pathogenic oomycetes, Phytophthora sojae and Aphanomyces cochlioides. To identify the antioomycete compounds produced by EPF, the extracts of 13 highly active EPF strains were characterized in detail by high performance liquid chromatography with diode array detection and high-resolution mass spectrometric detection and antioomycete assay."

Our news journalists obtained a quote from the research from Osaka University, "The antioomycete activity of several Metarhizium extracts was associated with previously isolated aurovertins, fungerin, N-(methyl-3-oxodec-6-enoyl)-2-pyrroline, and N-(methyl-3-oxodecanoyl)-2-pyrroline. The depsipeptide beauvericin was confirmed to be one of the active principles of three strains of Isaria tenuipes, which strongly inhibited mycelial growth of both P. sojae and A. cochlioides. Two known bioactive metabolites, paecilosetin and aranorosinol A, together with a novel and potent antioomycete compound, farinomalein, were isolated from the extracts of Isaria farinosa and all compounds were confirmed to have antioomycete activity."

According to the news editors, the research concluded: "Identification of 8 antioomycete compounds from 13 clavicipitioid EPF demonstrated a new potential use of EPF as a source of compounds for the control of soil-borne plant pathogenic oomycetes."

For more information on this research see: Production of antioomycete compounds active against the phytopathogens Phytophthora sojae and Aphanomyces cochlioides by clavicipitoid entomopathogenic fungi. Journal of Bioscience and Bioengineering, 2014;117(5):557-62. (Elsevier -; Journal of Bioscience and Bioengineering -

Our news journalists report that additional information may be obtained by contacting S.P. Putri, International Center for Biotechnology, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan. Additional authors for this research include K. Ishido, H. Kinoshita, S. Kitani, F. Ihara, Y. Sakihama, Y. Igarashi and T. Nihira (see also Life Science Research).

Keywords for this news article include: Asia, Osaka, Japan, Life Science Research.

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Source: Life Science Weekly

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