News Column

New Mycotoxins Study Findings Recently Were Reported by Researchers at Fujian Medical University

June 17, 2014



By a News Reporter-Staff News Editor at Life Science Weekly -- Data detailed on Biological Factors have been presented. According to news reporting originating in Fujian, People's Republic of China, by NewsRx journalists, research stated, "The selective detection of ultratrace amounts of ochratoxin A (OTA) is extremely important for food safety since it is one of the most toxic and widespread mycotoxin. Here we develop a signal-on fluorescent biosensor for detection of OTA based on fluorescent DNA-scaffolded silver-nanocluster (AgNCs), structure-switching of anti-OTA aptamer (Ap) and magnetic beads (MBs), and demonstrate its feasibility in the application of detecting OTA in real samples of wheat."

The news reporters obtained a quote from the research from Fujian Medical University, "The method exhibits superior sensitivity with a detection limit as low as 2 pg/mL OTA with high specificity. To the best of our knowledge, this is the first attempt to detect OTA based on DNA-scaffolded AgNCs, which possesses relatively high fluorescence quantum yield and photostability with regard to traditional organic dyes and quantum dots."

According to the news reporters, the research concluded: "Moreover, combined with the merits of MBs and aptamer, the proposed sensor has many advantages such as fabrication easiness, operation convenience, low cost, and being fast and portable, which may represent a promising path toward routine OTA control."

For more information on this research see: A fluorescent aptasensor based on DNA-scaffolded silver-nanocluster for ochratoxin A detection. Biosensors & Bioelectronics, 2014;57():226-31. (Elsevier - www.elsevier.com; Biosensors & Bioelectronics - www.elsevier.com/wps/product/cws_home/405913)

Our news correspondents report that additional information may be obtained by contacting J. Chen, Dept. of Pharmaceutical Analysis, Faculty of Pharmacy, Fujian Medical University, Fuzhou 350108, Fujian, People's Republic of China. Additional authors for this research include X. Zhang, S. Cai, D. Wu, M. Chen, S. Wang and J. Zhang (see also Biological Factors).

Keywords for this news article include: Asia, Fujian, Mycotoxins, Ochratoxins, DNA Research, Biological Factors, People's Republic of China.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Life Science Weekly


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