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New Findings on DNA Research Described by Investigators at Qingdao University of Science and Technology

June 17, 2014

By a News Reporter-Staff News Editor at Life Science Weekly -- Fresh data on DNA Research are presented in a new report. According to news reporting originating from Qingdao, People's Republic of China, by NewsRx correspondents, research stated, "A novel highly sensitive electrochemiluminescence (ECL) detection protocol for mercury(II) ions was developed. Based on the strong and stable thyminethymine mismatches complexes coordination chemistry, mercury(II) ions can specifically bind to a designed DNA strand, leading to the release of the complimentary DNA strand."

Our news editors obtained a quote from the research from the Qingdao University of Science and Technology, "The released DNA strand was then captured by magnetic beads modified with specific DNA, and then through the formation of DNA-linked luminol-Au nanoparticles (NPs) superstructure, a specific ECL system for mercury(II) ions was developed. Using 3-aminopropyl-triethoxysilane as an effective enhancer, the ECL system can detect Hg2+ ion within a linear range from 2.0x10(-10)molL(-1) to 2.0x10(-8)M, with a detection limit as low as 1.05x10(-10)M (3 sigma)."

According to the news editors, the research concluded: "Moreover, this ECL system is highly specific for Hg2+, without interference from other commonly coexisted metal ions, and it can be used for the analysis of real samples."

For more information on this research see: Highly Sensitive Electrochemiluminescence Detection of Mercury(II) Ions Based on DNA-Linked Luminol-Au NPs Superstructure. Electroanalysis, 2014;26(4):823-830. Electroanalysis can be contacted at: Wiley-V C H Verlag Gmbh, Boschstrasse 12, D-69469 Weinheim, Germany. (Wiley-Blackwell -; Electroanalysis -

The news editors report that additional information may be obtained by contacting J. Wan, Qingdao Univ Sci & Technol, Coll Chem & Mol Engn, Key Lab Sensor Anal Tumor Marker, Minist Educ, Qingdao 266042, People's Republic of China. Additional authors for this research include G. Yin, X.J. Ma, L. Xing and X.L. Luo (see also DNA Research).

Keywords for this news article include: Asia, Qingdao, DNA Research, People's Republic of China

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Life Science Weekly

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