News Column

New Findings from Clarkson University in Biosensing Provides New Insights

June 18, 2014



By a News Reporter-Staff News Editor at Biotech Week -- New research on Biosensing is the subject of a report. According to news reporting originating in Potsdam, New York, by NewsRx journalists, research stated, "The construction and characterization of a biosensor based on polymer brushes is reported. The use of polymer brushes combined with nanoparticles was applied to show its suitability as a biosensor platform - with glucose oxidase as an enzyme probe."

The news reporters obtained a quote from the research from Clarkson University, "The biosensor demonstrated a pH-sensitive on-off property, and it was further used to control or modulate the electrochemical responses. In terms of the kinetic behavior, we were able to show the changing in the kinetic parameters of glucose oxidase operating in on and off state of the polymer brushes. The performance of the bioelectrode was investigated by chronoamperometry, impedance electrochemistry and cyclic voltammetric techniques. At optimized experimental conditions the dynamic concentration range was 2.0 to 16.0mmolL(-1) with a detection limit of 5.6x10-(6) molL(-1). The repeatability of current responses for injections of 5.0mmolL(-1) glucose was evaluated to be 5.3% (n=10)."

According to the news reporters, the research concluded: "The resulting biosensor seemed to provide the enzymes with a biocompatible nanoenvironment as it sustained the enhanced enzyme activity for an extended time and promoted possible good electron transfer through the polymer brushes to the electrode."

For more information on this research see: Stimuli-Responsive Biointerface Based on Polymer Brushes for Glucose Detection. Electroanalysis, 2014;26(4):815-822. Electroanalysis can be contacted at: Wiley-V C H Verlag Gmbh, Boschstrasse 12, D-69469 Weinheim, Germany. (Wiley-Blackwell - www.wiley.com/; Electroanalysis - onlinelibrary.wiley.com/journal/10.1002/(ISSN)1521-4109)

Our news correspondents report that additional information may be obtained by contacting B.P. Crulhas, Clarkson University, Chem & Biomol Department, Potsdam, NY, United States. Additional authors for this research include J.R. Sempionatto, M.F. Cabral, S. Minko and V.A. Pedrosa (see also Biosensing).

Keywords for this news article include: Potsdam, New York, Biosensing, United States, Bioengineering, Bionanotechnology, Nanobiotechnology, North and Central America

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Biotech Week


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