News Column

New Findings from Australian National University Describe Advances in Drug Delivery Systems

June 18, 2014

By a News Reporter-Staff News Editor at Biotech Week -- Researchers detail new data in Drugs and Therapies. According to news reporting out of Canberra, Australia, by NewsRx editors, research stated, "Synthesis of magnetic Fe3O4/SiO2/graphene-CdTe QDs/chitosan nanocomposites (FGQCs) is investigated with respect to their potential of improving the drug loading content above that of magnetic/fluorescent bifunctional nanocomposites. To evaluate the performance of the FGQCs, their surface morphology was thoroughly assessed."

Our news journalists obtained a quote from the research from Australian National University, "The in vitro interaction between the FGQCs and heptoma cell line smmc-7721 cells was observed for the first time by TEM ultrathin section imaging. At an excitation wavelength of 365 nm, the graphene-QDs exhibit a strong luminescence in aqueous environments. The loading content and entrapment efficiency of the FGQCs were 70% and 50%, respectively. The cytotoxicity of this novel drug delivery system was evaluated in vitro using heptoma cell line smmc-7721 and quantified by the 3-(4,5-dimethylthiazol-z-yl)-2,5-diphenyltetrazolium bromide (MTT) assay."

According to the news editors, the research concluded: "The results show that FGQCs are a promising new multifunctional material for drug delivery in biological and medical applications."

For more information on this research see: Fabrication and cyto-compatibility of Fe3O4/SiO2/graphene-CdTe QDs/CS nanocomposites for drug delivery. Colloids and Surfaces B-Biointerfaces, 2014;117():466-472. Colloids and Surfaces B-Biointerfaces can be contacted at: Elsevier Science Bv, PO Box 211, 1000 Ae Amsterdam, Netherlands (see also Drugs and Therapies).

Our news journalists report that additional information may be obtained by contacting J. Ou, Australian National University, Res Sch Engn, Canberra, ACT 0200, Australia. Additional authors for this research include F. Wang, Y.J. Huang, D.S. Li, Y.M. Jiang, Q.H. Qin, Z.H. Stachurski, A. Tricoli and T.N. Zhang.

Keywords for this news article include: Canberra, Drugs and Therapies, Drug Delivery Systems, Australia and New Zealand

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Source: Biotech Week

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