News Column

New DNA Research Study Results from National Academy of Sciences Described

June 18, 2014



By a News Reporter-Staff News Editor at Biotech Week -- Investigators discuss new findings in DNA Research. According to news reporting from Taipei, Taiwan, by NewsRx journalists, research stated, "DNA mimic proteins have DNA-like negative surface charge distributions, and they function by occupying the DNA binding sites of DNA binding proteins to prevent these sites from being accessed by DNA. DNA mimic proteins control the activities of a variety of DNA binding proteins and are involved in a wide range of cellular mechanisms such as chromatin assembly, DNA repair, transcription regulation, and gene recombination."

The news correspondents obtained a quote from the research from the National Academy of Sciences, "However, the sequences and structures of DNA mimic proteins are diverse, making them difficult to predict by bioinformatic search. To date, only a few DNA mimic proteins have been reported. These DNA mimics were not found by searching for functional motifs in their sequences but were revealed only by structural analysis of their charge distribution. This review highlights the biological roles and structures of 16 reported DNA mimic proteins."

According to the news reporters, the research concluded: "We also discuss approaches that might be used to discover new DNA mimic proteins."

For more information on this research see: DNA Mimic Proteins: Functions, Structures, and Bioinformatic Analysis. Biochemistry, 2014;53(18):2865-2874. Biochemistry can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; Biochemistry - www.pubs.acs.org/journal/bichaw)

Our news journalists report that additional information may be obtained by contacting H.C. Wang, Academy Sinica, Core Facil Prot Struct Anal, Taipei 115, Taiwan. Additional authors for this research include C.H. Ho, K.C. Hsu, J.M. Yang and A.H.J. Wang (see also DNA Research).

Keywords for this news article include: Asia, Biotechnology, Taipei, Taiwan, Peptides, Proteins, Amino Acids, DNA Research, Bioengineering, Applied Bioinformatics

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Biotech Week


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