News Column

New Cancer Gene Therapy Study Findings Have Been Reported by Researchers at Huazhong University of Science and Technology

June 16, 2014



By a News Reporter-Staff News Editor at Cancer Gene Therapy Week -- A new study on Biotechnology is now available. According to news originating from Hubei, People's Republic of China, by NewsRx correspondents, research stated, "In previous a study, we had developed a novel thermosensitive magnetic delivery system based on liposomes. This study aimed to evaluate the efficiency of this system for the co-delivery of both drugs and genes to the same cell and its anti-tumor effects on gastric cancer."

Our news journalists obtained a quote from the research from the Huazhong University of Science and Technology, "Doxorubicin (DOX) and SATB1 shRNA vector were loaded into the co-delivery system, and in vitro DOX thermosensitive release activity, targeted gene silencing efficiency, targeted cellular uptake, in vitro cytotoxicity, as well as in vivo anti-tumor activity were determined. The results showed that this co-delivery system had desirable targeted delivery efficacy, DOX thermosensitive release and SATB1 gene silencing. Moreover, the co-delivery of DOX and SATB1 shRNA exhibited enhanced activity to inhibit gastric cancer cell growth in vitro and in vivo, compared to single delivery."

According to the news editors, the research concluded: "The novel thermosensitive magnetic drug and gene co-delivery system has promising application in combined chemotherapy and gene therapy for gastric cancer."

For more information on this research see: Co-delivery of doxorubicin and SATB1 shRNA by thermosensitive magnetic cationic liposomes for gastric cancer therapy. Plos One, 2014;9(3):e92924. (Public Library of Science - www.plos.org; Plos One - www.plosone.org)

The news correspondents report that additional information may be obtained from Z. Peng, Gastrointestinal Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People's Republic of China. Additional authors for this research include C. Wang, E. Fang, X. Lu, G. Wang and Q. Tong (see also Biotechnology).

Keywords for this news article include: Asia, Biotechnology, Hubei, Genetics, Oncology, Liposomes, Gastric Cancer, Gastroenterology, Cancer Gene Therapy, Drug Delivery Systems, People's Republic of China.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Cancer Gene Therapy Week


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