News Column

Findings on Streptococcus Reported by Investigators at Hunan University

June 17, 2014

By a News Reporter-Staff News Editor at Life Science Weekly -- Fresh data on Gram-Positive Bacteria are presented in a new report. According to news reporting originating from Changsha, People's Republic of China, by NewsRx correspondents, research stated, "Rapid and accurate detection of Group A Streptococcus (GAS) infection is very important in clinical diagnosis. In this paper, a new aptamer/SWNTs interdigital gold electrode piezoelectric sensor was constructed for detection of GAS."

Our news editors obtained a quote from the research from Hunan University, "The selected anti-GAS aptamer was used as recognition probe and single-walled carbon nanotubes (SWNTs) immobilized on the Interdigital Gold Electrode (IDE) was used as electron transducer which connected to piezoelectric quartz crystal (SPQC) in series. The response mechanism of constructed sensor was based on the fact that GAS specifically reacted with anti-GAS aptamer immobilized on SWNTs IDE and caused aptamer detaching from SWNTs IDE and resulted sensitively frequency shift response of IDE-SPQC. The frequency shift of constructed sensor had a linear relationship with the concentration of GAS in the range of 3 Chi 10(6) cfu/ml to 3 Chi 10(6) cfu/ml. The detection limit was 12 cfu/ml GAS. The detection time was less than 40 min. The recovery rate for detection of GAS in milk was 76-97% using constructed sensor."

According to the news editors, the research concluded: "It would find application in clinical diagnosis and environment for rapid detection of GAS."

For more information on this research see: A new aptamer/SWNTs IDE-SPQC sensor for rapid and specific detection of Group A Streptococcus. Sensors and Actuators B-Chemical, 2014;198():431-437. Sensors and Actuators B-Chemical can be contacted at: Elsevier Science Sa, PO Box 564, 1001 Lausanne, Switzerland (see also Gram-Positive Bacteria).

The news editors report that additional information may be obtained by contacting X.H. Shi, Hunan Univ, Coll Chem & Chem Engn, State Key Lab Chemo Biosensing & Chemometr, Changsha 410082, Hunan, People's Republic of China. Additional authors for this research include F.J. He, Y. Lian, D.Y. Yan and X.Q. Zhang.

Keywords for this news article include: Asia, Changsha, Streptococcus, Streptococcaceae, Gram-Positive Cocci, Gram-Positive Bacteria, People's Republic of China

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Source: Life Science Weekly

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