News Column

Findings from J. Guan and Co-Researchers Provides New Data on Peroxidases

June 17, 2014

By a News Reporter-Staff News Editor at Life Science Weekly -- Data detailed on Enzymes and Coenzymes have been presented. According to news reporting from Shandong, People's Republic of China, by NewsRx journalists, research stated, "The interactions between well-dispersed multiwalled carbon nanotubes (MWCNTs) and catalase (CAT) were investigated. The activity of CAT was inhibited with the addition of MWCNTs."

The news correspondents obtained a quote from the research, "After deducting the inner filter effect, the fluorescence spectra revealed that the tryptophan (Trp) residues were exposed and the fluorescence intensities of CAT increased with the increase in the MWCNTs concentration. At the same time, the environment of the Trp residues became more hydrophobic. The results of UV-vis absorption spectroscopy and CD spectra indicated that the secondary structure of CAT had been changed, and the amino acid residues were located in a more hydrophobic environment. Meanwhile, the UV-vis spectra indicated that the conformation of the heme porphyrin rings was changed. The microenvironment of CAT activity sites may be interfered by MWCNTs."

According to the news reporters, the research concluded: "This research showed that MWCNTs could not only contribute to the conformational changes of protein but also change the enzyme function."

For more information on this research see: Spectroscopic Investigations on the Interaction between Carbon Nanotubes and Catalase on Molecular Level. Journal of Biochemical and Molecular Toxicology, 2014;28(5):211-216. Journal of Biochemical and Molecular Toxicology can be contacted at: Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ, USA. (Wiley-Blackwell -; Journal of Biochemical and Molecular Toxicology -

Our news journalists report that additional information may be obtained by contacting J. Guan, Shandong Environm Monitoring Center, Jinan 250101, Shandong, People's Republic of China. Additional authors for this research include J.P. Dai, X.C. Zhao, C.H. Liu, C.Z. Gao and R.T. Liu (see also Enzymes and Coenzymes).

Keywords for this news article include: Asia, Shandong, Catalase, Enzymology, Fullerenes, Peroxidases, Carbon Nanotubes, Enzymes and Coenzymes, People's Republic of China

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Life Science Weekly

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