News Column

Data from J. Tanne and Colleagues Advance Knowledge in Hemeproteins

June 17, 2014

By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on Proteins. According to news reporting originating in Teltow, Germany, by NewsRx journalists, research stated, "The development of a new surface architecture for the efficient direct electron transfer of positively charged redox proteins is presented. For this reason different kinds of polyaniline terpolymers consisting of aminobenzoic acid (AB), aminobenzenesulfonic acid (ABS) and aniline (A) with different monomer ratios were synthesized."

The news reporters obtained a quote from the research, "The P(AB-ABS-A) were grafted to the surface of multiwalled carbon nanotubes (MWCNTs). FTIR measurements prove the covalent binding to the carboxylic groups of the MWCNTs while conductivity tests show an increase in the conductivity of the nanohybrid in comparison to the polymers. The [MWCNT-P(AB-ABS-A)] nanohybrids were used for the immobilization of redox active cytochrome c (cyt.c). The positively charged protein can electrostatically interact with the negatively charged nanohybrid. Cyclic voltammetry (CV) shows an increase in the protein loading on [MWCNT-P(AB-ABS-A)] coupled to cysteamine modified gold electrodes in comparison to non-grafted MWCNTs. A further increase in the sulfonation degree of P(AB-ABS-A) leads to an enhanced current output of the modified electrodes. The redox activity of the polymer decreases after the immobilization of the cyt.c on the nanohybrid."

According to the news reporters, the research concluded: "For the first time polymers covalently grafted to the surface of MWCNTs are used in a biosensor."

For more information on this research see: Nanohybrid Materials Consisting of Poly[(3-aminobenzoic acid)-co-(3-aminobenzenesulfonic acid)-co-aniline] and Multiwalled Carbon Nanotubes for Immobilization of Redox Active Cytochrome c. Electroanalysis, 2014;26(4):732-738. Electroanalysis can be contacted at: Wiley-V C H Verlag Gmbh, Boschstrasse 12, D-69469 Weinheim, Germany. (Wiley-Blackwell -; Electroanalysis -

Our news correspondents report that additional information may be obtained by contacting J. Tanne, Inst Thin Film & Microsensor Technol, D-14513 Teltow, Germany. Additional authors for this research include B. Dietzel, F.W. Scheller and F. Bier (see also Proteins).

Keywords for this news article include: Teltow, Europe, Germany, Fullerenes, Cytochromes, Hemeproteins, Nanotechnology, Carbon Nanotubes, Aminobenzoic Acids, Emerging Technologies

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Life Science Weekly

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