ENP Newswire -
Release date- 09062014 - Stem cells are special because they are essential to the normal function of our organs and tissues.
Previous research shows stem cells grown on hard substrates go on to multiply but do not differentiate: a process by which the cells specialise to perform specific functions in the body. In contrast, stem cells grown on softer surfaces do go on to differentiate.
In this new study, published in the journal
'By changing the surface properties like the shape of the substrate at the nanoscale level, we tricked the stem cells to behave differently,' explains co-author Dr
The team tested different sizes of the nanopatches - from 3 microns to 100 nanometres (about one thousandth of the diameter of a hair). The stem cells behaved as if they were on a soft surface when in contact with the smallest patches because they can't firmly grip them.
Dr Gautrot added: 'This development will be useful when there's a need to create a rigid implant to be inserted into the body. Potentially, such nanopatches could provide a soft touch to the surface of the implant so that cells from the neighbouring tissues are not perturbed by such a hard material.'
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