News Column

Study Results from Chinese Academy of Science Broaden Understanding of Salmonella Infections

May 14, 2014



By a News Reporter-Staff News Editor at Biotech Week -- Fresh data on Gram-Negative Bacterial Infections are presented in a new report. According to news reporting from Guangdong, People's Republic of China, by NewsRx journalists, research stated, "Convenient and sensitive point-of-care rapid diagnostic tests for food-borne pathogens have been a long-felt need of clinicians. Traditional approaches such as culture-based methods have good sensitivity and specificity, but they tend to be tedious and time-consuming."

The news correspondents obtained a quote from the research from the Chinese Academy of Science, "Herein we present a simple and sensitive aptamer based biosensor for rapid detection of Salmonella enteritidis (S. enteritidis). One of the aptamers specific for the outmembrane of S. enteritidis was used for magnetic bead enrichments. Another aptamer against S. enteritidis was used as a reporter for this pathogen, which was amplified by isothermal strand displacement amplification (SDA) and further detected by a lateral flow biosensor. As low as 10(1) colony forming unit (CFU) of S. enteritidis was detected in this study."

According to the news reporters, the research concluded: "Without DNA extraction, the reduced handling and simpler equipment requirement render this assay a simple and rapid alternative to conventional methods."

For more information on this research see: Lateral flow biosensor for DNA extraction-free detection of salmonella based on aptamer mediated strand displacement.amplification. Biosensors & Bioelectronics, 2014;56():192-197. Biosensors & Bioelectronics can be contacted at: Elsevier Advanced Technology, Oxford Fulfillment Centre The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. (Elsevier - www.elsevier.com; Biosensors & Bioelectronics - www.elsevier.com/wps/product/cws_home/405913)

Our news journalists report that additional information may be obtained by contacting Z.Y. Fang, Chinese Academy Sci, Guangzhou Inst Biomed & Hlth, Key Lab Regenerat Biol, Guangzhou 510530, Guangdong, People's Republic of China. Additional authors for this research include W. Wu, X.W. Lu and L.W. Zeng (see also Gram-Negative Bacterial Infections).

Keywords for this news article include: Asia, Guangdong, Biosensing, DNA Research, Salmonellosis, Bioengineering, Bionanotechnology, Nanobiotechnology, Gammaproteobacteria, Salmonella Infections, People's Republic of China, Enterobacteriaceae Infections, Gram-Negative Bacterial Infections, Gram-Negative Facultatively Anaerobic Rods

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Biotech Week


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