News Column

Reports from J.M. Mudrik and Co-Researchers Add New Data to Findings in Proteomics

May 13, 2014

By a News Reporter-Staff News Editor at Life Science Weekly -- A new study on Proteomics is now available. According to news reporting from Toronto, Canada, by NewsRx journalists, research stated, "We present the first method for digital microfluidics-based strong cation-exchange solid-phase extractions. Digital microfluidics is a microscale fluid handling technique in which liquid droplets are actuated over an array of electrodes by electrodynamic forces."

The news correspondents obtained a quote from the research, "Strong cation exchange has gained considerable importance in the field of proteomics as a separation mode for protein and peptide extractions. The marriage of these two techniques is achieved by incorporating sulphonate-functionalised porous polymer monolith discs onto digital microfluidic chips. By manipulating sample and solvent droplets onto and off of these porous polymer monoliths, proteins and peptides are extracted by controlling solution pH and ionic strength. This novel microscale extraction method has efficiency comparable to commercially available strong cationexchange ZipTips and is highly effective for sample cleanup."

According to the news reporters, the research concluded: "We anticipate that this digital microfluidic strong cationexchange extraction technique will prove useful for microscale proteomic analyses and other applications requiring separation of cationic compounds."

For more information on this research see: Strong and small: strong cation-exchange solid-phase extractions using porous polymer monoliths on a digital microfluidic platform. Canadian Journal of Chemistry-Revue Canadienne De Chimie, 2014;92(3):179-185. Canadian Journal of Chemistry-Revue Canadienne De Chimie can be contacted at: Canadian Science Publishing, Nrc Research Press, 65 Auriga Dr, Suite 203, Ottawa, On K2E 7W6, Canada (see also Proteomics).

Our news journalists report that additional information may be obtained by contacting J.M. Mudrik, Donnelly Center Cellular & Biomol Res, Toronto, ON M5S 3E1, Canada. Additional authors for this research include M.D.M. Dryden, N.M. Lafreniere and A.R. Wheeler.

Keywords for this news article include: Canada, Toronto, Ontario, Proteomics, North and Central America

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Source: Life Science Weekly