News Column

New Glycopeptides Study Results Reported from Department of Materials Science & Engineering

May 14, 2014

By a News Reporter-Staff News Editor at Biotech Week -- Investigators publish new report on Peptides. According to news reporting out of Yongin, South Korea, by NewsRx editors, research stated, "Conjugation of antibiotic vancomycin (VAN) on nanoparticles (NPs) has recently initiated novel works in the nanobiotechnology field. In this study, a bioelectronic structure using VAN conjugated zinc oxide (ZnO) NPs as charge storing elements on metal-pentacene-insulator-silicon (MPIS) device is demonstrated."

Our news journalists obtained a quote from the research from the Department of Materials Science & Engineering, "Highly specific molecular recognition between the VAN and membrane protein unit mimicked from VAN-resistant bacteria is employed as the formation mechanism of self-assembly monolayers (SAMs) of ZnO NPs. The insulator surface is modified with the VAN cognate peptide of L-Ala-o-Glu-L-Lys-D-Ala-D-Ala by chemical activator coupling. Hysteretic behaviors in capacitance versus voltage (C-V) curves are obtained for the charged ZnO NPs exhibiting flatband voltage shifts, which demonstrate the charge storage on the VAN conjugated ZnO NPs."

According to the news editors, the research concluded: "The potential perspective of this study will be a tangible progress of biomolecular electronics implemented by the interface between biomolecules and electronics."

For more information on this research see: Robust ZnO nanoparticle embedded memory device using vancomycin conjugate and its biorecognition for electrical charging node. Biosensors & Bioelectronics, 2014;56():33-38. Biosensors & Bioelectronics can be contacted at: Elsevier Advanced Technology, Oxford Fulfillment Centre The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. (Elsevier -; Biosensors & Bioelectronics -

Our news journalists report that additional information may be obtained by contacting M. Kim, Myongii Univ, Dept. of Mat Sci & Engn, Yongin 449728, South Korea. Additional authors for this research include H.J. Lee, S. Oh, Y. Kim, H. Jung, M.K. Oh, Y.J. Yoon, T.H. Yoo, T.S. Yoon and H.H. Lee (see also Peptides).

Keywords for this news article include: Asia, Yongin, Vancomycin, South Korea, Electronics, Glycopeptides

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Source: Biotech Week

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