By a News Reporter-Staff News Editor at Journal of Engineering -- Current study results on Chemical Engineering have been published. According to news originating from Troy, New York, by VerticalNews correspondents, research stated, "Optimization of the operating parameters for membrane separation of proteins is usually performed in industry by varying one factor at a time. While this procedure cannot ensure that an optimum is found, it is generally too time-consuming and costly to determine optimal operating conditions by simultaneously varying all factors."
Our news journalists obtained a quote from the research from Rensselaer Polytechnic Institute, "This paper presents a procedure that can be generically used by, for example, the biotechnology industry, for determining close to optimal operating conditions for cases where relatively little data are available. The procedure fits a polynomial regression model to the operating parameters and performs a multidimensional optimization of the empirical model with regard to some important operating parameter, for example, a combination of selectivity and purity."
According to the news editors, the research concluded: "The technique is illustrated with a membrane ultrafiltration process for the separation of hen egg lysozyme from ribonuclease A and in a second case study for separating hemoglobin from bovine serum albumin."
For more information on this research see: Optimization of Membrane Separation Processes for Protein Fractionation. Industrial & Engineering Chemistry Research, 2014;53(13):5103-5109. Industrial & Engineering Chemistry Research can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; Industrial & Engineering Chemistry Research - www.pubs.acs.org/journal/iecred)
The news correspondents report that additional information may be obtained from A.S. Bhadouria, Rensselaer Polytechnic Inst, Center Biotechnol & Interdisciplinary Studies, Troy, NY 12180, United States. Additional authors for this research include M. Sorci, M.H. Gu, G. Belfort and J. Hahn.
Keywords for this news article include: Troy, New York, United States, Chemical Engineering, North and Central America
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