News Column

New Biotechnology Study Results Reported from Delft University of Technology

May 14, 2014

By a News Reporter-Staff News Editor at Biotech Week -- Investigators publish new report on Technology. According to news reporting out of Delft, Netherlands, by NewsRx editors, research stated, "The purification of biopharmaceuticals is commonly considered the bottleneck of the manufacturing process. Increasing product diversity, along with growing regulatory and economic constraints raise the need to adopt new rational, systematic, and generally applicable process development strategies."

Our news journalists obtained a quote from the research from the Delft University of Technology, "Liquid chromatography is the key step in most purification processes and a well-understood unit operation, yet this understanding is still rarely effectively utilized during process development. Knowledge of the composition of the mixture, the molecular properties of the solutes and how they interact with the resins are required to rationalise the design choices."

According to the news editors, the research concluded: "Here, we provide an overview of the advances in the determination and measurement of these properties and interactions, and outline their use throughout the different stages of downstream process development."

For more information on this research see: Purifying biopharmaceuticals: knowledge-based chromatographic process development. Trends in Biotechnology, 2014;32(4):210-220. Trends in Biotechnology can be contacted at: Elsevier Science London, 84 Theobalds Rd, London WC1X 8RR, England. (Elsevier -; Trends in Biotechnology -

Our news journalists report that additional information may be obtained by contacting A.T. Hanke, Delft University of Technology, Dept. of Biotechnol, Delft, Netherlands (see also Technology).

Keywords for this news article include: Delft, Europe, Technology, Netherlands

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Biotech Week

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