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Findings on Molecular Biology Detailed by Investigators at Chinese Academy of Science

June 3, 2014

By a News Reporter-Staff News Editor at Life Science Weekly -- Researchers detail new data in Life Science Research. According to news reporting from Beijing, People's Republic of China, by NewsRx journalists, research stated, "Antidepressants are a new kind of pollutants being increasingly found in wastewater. In this study, a fast and sensitive ultra-high performance liquid chromatography-tandem mass spectrometry method was developed and validated for the analysis of 24 antidepressant drugs and six of their metabolites in wastewater."

The news correspondents obtained a quote from the research from the Chinese Academy of Science, "This is the first time that the antidepressant residues in wastewater of Beijing (China) were systematically reported. A solid-phase extraction process was performed with 3 M cation disk, followed by ultra-high performance liquid chromatography-tandem mass spectrometry measurements. The chromatographic separation and mass parameters were optimized in order to achieve suitable retention time and good resolution for analytes. All compounds were satisfactorily determined in one single injection within 20 min. The limit of quantification (LOQ), linearity, and extraction recovery were validated. The LOQ for analytes were ranged from 0.02 to 0.51 ng/mL. The determination coefficients were more than 0.99 within the tested concentration range (0.1-25 ng/mL), and the recovery rate for each target compound was ranged from 81.2% to 118% at 1 ng/mL. This new developed method was successfully applied to analysis the samples collected from Beijing municipal wastewater treatment plants."

According to the news reporters, the research concluded: "At least ten target antidepressants were found in all samples and the highest mean concentration of desmethylvenlafaxin was up to 415.6 ng/L."

For more information on this research see: Simultaneous Determination of 24 Antidepressant Drugs and Their Metabolites in Wastewater by Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry. Molecules, 2014;19(1):1212-1222. Molecules can be contacted at: Mdpi Ag, Postfach, Ch-4005 Basel, Switzerland. (Springer -; Molecules -

Our news journalists report that additional information may be obtained by contacting L.H. Sheng, Chinese Academy Sci, Ecoenvironm Sci Res Center, Beijing 100085, People's Republic of China. Additional authors for this research include H.R. Chen, Y.B. Huo, J. Wang, Y. Zhang, M. Yang and H.X. Zhang (see also Life Science Research).

Keywords for this news article include: Asia, Beijing, Imaging Technology, Life Science Research, People's Republic of China, High-Performance Liquid Chromatography

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Life Science Weekly

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