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Findings on Amino Acids Detailed by Researchers at Department of Biological Chemistry

June 3, 2014

By a News Reporter-Staff News Editor at Life Science Weekly -- Research findings on Amino Acids are discussed in a new report. According to news reporting originating from Kolkata, India, by NewsRx correspondents, research stated, "Self-assembled bolaamphiphilic perylene bisimide (PBI) containing an amino acid appended fluorescent semiconducting soft material (hydrogel) has been discovered at physiological pH. This new organic material based on self-assembled perylene bisimide appended amino acid-based bolaamphiphile (PBI-C11-Y) has been well characterized using various techniques including UV-Vis, fluorescence, X-ray diffraction, FT-IR, transmission electron microscopic (TEM) and atomic force microscopic (AFM) studies."

Our news editors obtained a quote from the research from the Department of Biological Chemistry, "Interestingly, the UV-Vis absorption properties of the soft-material are dependent on the pH of the medium. This PBI-conjugated amino acid appended gelator molecule contains a centrally located perylene bisimide moiety as well as an aromatic amino acid l-tyrosine at the side chains, which are extremely useful for interacting with the delocalized large ?-surface of GO (graphene oxide) or RGO (reduced graphene oxide) to form a GO/RGO containing hybrid hydrogel. Graphene oxide and reduced graphene oxide have been successfully incorporated into the nanofibrillar network structure of the PBI-C11-Y based gel to make nanohybrid systems. The I-V profile of the semiconducting photo-responsive soft-material of the PBI-C11-Y has been successfully tuned upon the incorporation of GO and RGO within the gel-based soft material. This PBI-C11-Y xerogel based structure shows photo-switching behaviour upon exposure to white light. The ON/OFF ratio of the PBI-C11-Y can be modulated upon the inclusion of GO and RGO within the hydrogel matrix. Furthermore, the OFF state stability of the PBI-C11-Y xerogel material has been increased upon the inclusion of RGO."

According to the news editors, the research concluded: "Regulation of the photo-switching behaviour of the PBI-C11-Y based xerogel holds promise for making PBI-containing amino acid appended biomaterials with interesting properties in future."

For more information on this research see: A bolaamphiphilic amino acid appended photo-switching supramolecular gel and tuning of photo-switching behaviour. Physical Chemistry Chemical Physics, 2014;16(13):6041-9. (Royal Society of Chemistry -; Physical Chemistry Chemical Physics -

The news editors report that additional information may be obtained by contacting S. Roy, Dept. of Biological Chemistry, Indian Association for the Cultivation of Science, Jadavpur, Kolkata 700032, India. Additional authors for this research include D.K. Maiti, S. Panigrahi, D. Basak and A. Banerjee (see also Amino Acids).

Keywords for this news article include: Asia, India, Kolkata, Alcohols, Hydrogel, Peptides, Proteins, Amino Acids, Nanotechnology, Supramolecular, Organic Chemicals, Polyethylene Glycols, Emerging Technologies.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Life Science Weekly

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