By a News Reporter-Staff News Editor at Life Science Weekly -- Data detailed on Nanoparticles have been presented. According to news reporting out of Mawson Lakes, Australia, by NewsRx editors, research stated, "Infections arising from bacterial adhesion and colonization on medical device surfaces are a significant healthcare problem. Silver based antibacterial coatings have attracted a great deal of attention as a potential solution."
Our news journalists obtained a quote from the research from the University of South Australia, "This paper reports on the development of a silver nanoparticles based antibacterial surface that can be applied to any type of material surface. The silver nanoparticles were surface engineered with a monolayer of 2-ercaptosuccinic acid, which facilitates the immobilization of the nanoparticles to the solid surface, and also reduces the rate of oxidation of the nanoparticles, extending the lifetime of the coatings. The coatings had excellent antibacterial efficacy against three clinically significant pathogenic bacteria i.e. Staphylococcus epidermidis, Staphylococcus aureus and Pseudomonas aeruginosa. Studies with primary human fibroblast cells showed that the coatings had no cytotoxicity in vitro. Innate immune studies in cultures of primary macrophages demonstrated that the coatings do not significantly alter the level of expression of pro-inflammatory cytokines or the adhesion and viability of these cells."
According to the news editors, the research concluded: "Collectively, these coatings have an optimal combination of properties that make them attractive for deposition on medical device surfaces such as wound dressings, catheters and implants."
For more information on this research see: Substrate independent silver nanoparticle based antibacterial coatings. Biomaterials, 2014;35(16):4601-4609. Biomaterials can be contacted at: Elsevier Sci Ltd, The Boulevard, Langford Lane, Kidlington, Oxford OX5 1GB, Oxon, England. (Elsevier - www.elsevier.com; Biomaterials - www.elsevier.com/wps/product/cws_home/30392)
Our news journalists report that additional information may be obtained by contacting S. Taheri, University of South Australia, Mawson Inst, Mawson Lakes, SA 5095, Australia. Additional authors for this research include A. Cavallaro, S.N. Christo, L.E. Smith, P. Majewski, M. Barton, J.D. Hayball and K. Vasilev (see also Nanoparticles).
Keywords for this news article include: Mawson Lakes, Nanotechnology, Emerging Technologies, Australia and New Zealand
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