News Column

Researchers at University of Malaya Report Findings in Amino Acids

May 27, 2014

By a News Reporter-Staff News Editor at Journal of Technology -- Investigators publish new report on Amino Acids. According to news originating from Kuala Lumpur, Malaysia, by VerticalNews correspondents, research stated, "Quorum sensing is a unique bacterial communication system which permits bacteria to synchronize their behaviour in accordance with the population density. The operation of this communication network involves the use of diffusible autoinducer molecules, termed N-acylhomoserine lactones (AHLs). Serratia spp. are well known for their use of quorum sensing to regulate the expression of various genes."

Our news journalists obtained a quote from the research from the University of Malaya, "In this study, we aimed to characterized the AHL production of a bacterium designated as strain RB-25 isolated from a former domestic waste landfill site. It was identified as Serratia fonticola using matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry analysis and this was confirmed by 16S ribosomal DNA sequencing. High resolution triple quadrupole liquid chromatography-mass spectrometry analysis of S. fonticola strain RB-25 spent culture supernatant indicated the existence of three AHLs namely: N-butyryl-L-homoserine lactone (C4-HSL), N-hexanoyl-L-homoserine lactone (C6-HSL) and N-(3-oxohexanoyl) homoserine-lactone (3-oxo-C6 HSL)."

According to the news editors, the research concluded: "This is the first report of the production of these AHLs in S."

For more information on this research see: Quorum sensing activity of Serratia fonticola strain RB-25 isolated from an ex-landfill site. Sensors, 2014;14(3):5136-46. (Elsevier -; Sensors -

The news correspondents report that additional information may be obtained from R. Ee, Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia. Additional authors for this research include Y.L. Lim, K.K. Tee, W.F. Yin and K.G Chan.

Keywords for this news article include: Asia, Malaysia, Homoserine, Amino Acids, Kuala Lumpur.

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Source: Journal of Technology

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