By a News Reporter-Staff News Editor at Science Letter -- Investigators publish new report on Science. According to news reporting out of Buffalo, New York, by NewsRx editors, research stated, "Brownian dynamics simulation is employed to examine the structure changes of complexes composed of a hydrophobic nanoparticle and a multiblock copolymer molecule (MCP). The dependence of the structure transitions on the radius of the nanoparticle, on the interactions between the hydrophobic segments of the MCP, and on the interactions between the hydrophobic segments and hydrophobic nanoparticle is examined."
Our news journalists obtained a quote from the research from the State University of New York, "It is shown that the multiblock copolymer adsorbed on a nanoparticle can acquire the structure of a micelle.To better characterize the micelle generated and the structure changes in the nanoparticle-MCP complex, the mass dipole moment of the complex [the distance between the center of mass of MCP and the center of the nanoparticle minus the radius of the nanoparticle (DCC)], the density profiles of MCP segments around its center of mass and around the nanoparticle, the radius of gyration of the MCP, and the thickness of the micelle around the nanoparticle are determined. It was found that, when structural transition of the complex occurs, the above quantities change dramatically."
According to the news editors, the research concluded: "The present simulation may provide new insights regarding the drug-loaded micelle interacting with a virus represented by a nanoparticle."
For more information on this research see: Micellar Structures in Nanoparticle-Multiblock Copolymer Complexes. Langmuir, 2014;30(13):3723-3728. Langmuir can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; Langmuir - www.pubs.acs.org/journal/langd5)
Our news journalists report that additional information may be obtained by contacting H.Y. Chen, SUNY Buffalo, Dept. of Chem & Biol Engn, Buffalo, NY 14260, United States (see also Science).
Keywords for this news article include: Buffalo, Science, New York, United States, North and Central America
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