News Column

Findings from University of Jinan Broaden Understanding of Fullerenes

May 30, 2014



By a News Reporter-Staff News Editor at Science Letter -- A new study on Fullerenes is now available. According to news reporting from Jinan, People's Republic of China, by NewsRx journalists, research stated, "A facile and sensitive electrochemiluminescence (ECL) immunosensor for the detection of human carcinoembryonic antigen (CEA) was designed. The immunosensor used Pt nanoparticles dotted graphene-carbon nanotubes composites (Pt/Gr-CNTs) as a platform and carbon dots functionalized Pt/Fe nanoparticles (Pt/Fe@CDs) as bionanolabels."

The news correspondents obtained a quote from the research from the University of Jinan, "The Pt/Gr-CNTs was first synthesized using a facile ultrasonic method to modify the working electrode, which increases the surface area to capture a large amount of primary anti-CEA antibodies as well as improving the electronic transmission rate. The bionanolabels Pt/Fe@CDs prepared through ethanediamine linking, showed good ECL signal amplification performance. The reason is that the Pt/Fe@CDs nanocomposites as signal tags can increase CDs loading per immunoreaction in comparison with single CDs. The approach provided a good linear response range from 0.003 to 600 ng mL(-1) with a low detection limit of 0.8 pg mL(-1). The immunosensor showed good specificity, acceptable stability and reproducibility. Satisfactory results were obtained in the determination of CEA in human serum albumin samples."

According to the news reporters, the research concluded: "Hence, the proposed ECL immunosensor could become a promising method for tumor marker detection."

For more information on this research see: A dual amplification strategy for ultrasensitive electrochemiluminescence immunoassay based on a Pt nanoparticles dotted graphene-carbon nanotubes composite and carbon dots functionalized mesoporous Pt/Fe. Analyst, 2014;139(7):1713-20. (Royal Society of Chemistry - www.rsc.org/; Analyst - pubs.rsc.org/en/journals/journalissues/an)

Our news journalists report that additional information may be obtained by contacting W. Deng, Key Laboratory of Chemical Sensing & Analysis in the University of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, People's Republic of China. Additional authors for this research include F. Liu, S. Ge, J. Yu, M. Yan and X. Song (see also Fullerenes).

Keywords for this news article include: Asia, Jinan, Fullerenes, Nanoparticle, Nanotechnology, Carbon Nanotubes, Emerging Technologies, People's Republic of China.

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC


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Source: Science Letter


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