Agreement Provides Exclusive Rights for Manufacturing and
Distribution of Plant ZFN Reagents
INDIANAPOLIS & ST. LOUIS--(BUSINESS WIRE)--
Dow AgroSciences LLC, a wholly owned subsidiary of The Dow Chemical
Company (NYSE: DOW), and Sigma-Aldrich Corporation (NASDAQ: SIAL)
announced today an exclusive manufacturing license and supply agreement
that will allow Sigma-Aldrich to manufacture and supply zinc finger
nuclease (ZFN) reagents for use with EXZACTTM Precision
Technology. Under the terms of the agreement, Sigma-Aldrich will be the
exclusive provider of ZFN reagents for use in plants which will be
available to Dow AgroSciences, its affiliates and licensees of the
EXZACT Precision Technology to enable precision transformation, trait
stacking and targeted mutagenesis in plants.
The EXZACT Precision Technology is a versatile and comprehensive
multi-technology platform that enables targeted genome modification in
plants. These technologies have been developed by Dow AgroSciences for
use in plants. A core component of the platform is Sangamo Biosciences
Inc.’s proprietary zinc finger technology, which Dow AgroSciences has
licensed exclusively for use in plants with the ability to broadly
sublicense to others in the plant technology space.
“Sigma-Aldrich was the partner of choice given its existing expertise in
manufacturing ZFN reagents as part of the CompoZr® platform
and excellent reputation for servicing clients in the Life Sciences
market,” says Daniel R. Kittle, Ph.D., Vice President, Research &
Development, Dow AgroSciences. “This exclusive manufacturing and supply
agreement marks an important milestone for DAS and its licensees,
securing much-needed additional capacity and a competitive cost position
for ZFN reagents. This is critical as the EXZACT Precision Technology is
deployed in product development.”
“Sigma-Aldrich is excited to support Dow AgroSciences in their decision
to integrate ZFNs into their seeds and traits pipeline,” said Shawn
Shafer, Functional Genomics Market Segment Manager at Sigma-Aldrich. “As
the first company to commercially distribute these products,
Sigma-Aldrich is pleased to be their manufacturer of choice, providing
Dow AgroSciences and Dow AgroSciences licensees with validated genome
editing reagents built on the same platform as our gold standard CompoZr
ZFNs. The ability to make precise genetic changes in plants will benefit
researchers and consumers alike."
Financial terms of the agreement were not disclosed.
About Dow AgroSciences
Dow AgroSciences, based in Indianapolis, Indiana, USA, is committed to
discovering, developing, and bringing to market crop protection and
plant biotechnology solutions for the growing world. Dow AgroSciences is
a wholly owned subsidiary of The Dow Chemical Company and had annual
global sales of $7.1 billion in 2013. Learn more at www.dowagro.com.
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Sigma-Aldrich and CompoZr are registered trademarks of Sigma-Aldrich Co.
®™Trademarks of The Dow Chemical Company (“Dow”) or an affiliated
company of Dow.
Kenda Resler Friend, 317-337-4743
Source: Dow AgroSciences LLC