News Column

Study Data from V. Zlateski and Colleagues Update Understanding of Enzymes and Coenzymes

May 27, 2014



By a News Reporter-Staff News Editor at Life Science Weekly -- Investigators publish new report on Enzymes and Coenzymes. According to news reporting originating in Zurich, Switzerland, by NewsRx journalists, research stated, "In the pursuit of robust and reusable biocatalysts for industrial synthetic chemistry, nanobiotechnology is currently taking a significant part. Recently, enzymes have been immobilized on different nanoscaffold supports."

The news reporters obtained a quote from the research, "Carbon coated metallic nanoparticles were found to be a practically useful support for enzyme immobilization due to their large surface area, high magnetic saturation, and manipulatable surface chemistry. In this study carbon coated cobalt nanoparticles were chemically functionalized (diazonium chemistry), activated for bioconjugation (N,N-disuccinimidyl carbonate), and subsequently used in enzyme immobilization. Three enzymes, beta-glucosidase, alpha-chymotrypsin, and lipase B were successfully covalently immobilized on the magnetic nonsupport."

According to the news reporters, the research concluded: "The enzyme-particle conjugates formed retained their activity and stability after immobilization and were efficiently recycled from milliliter to liter scales in short recycle times."

For more information on this research see: Efficient Magnetic Recycling of Covalently Attached Enzymes on Carbon-Coated Metallic Nanomagnets. Bioconjugate Chemistry, 2014;25(4):677-684. Bioconjugate Chemistry can be contacted at: Amer Chemical Soc, 1155 16TH St, NW, Washington, DC 20036, USA. (American Chemical Society - www.acs.org; Bioconjugate Chemistry - www.pubs.acs.org/journal/bcches)

Our news correspondents report that additional information may be obtained by contacting V. Zlateski, TurboBeads GmbH, CH-8050 Zurich, Switzerland. Additional authors for this research include R. Fuhrer, F.M. Koehler, S. Wharry, M. Zeltner, W.J. Stark, T.S. Moody and R.N. Grass (see also Enzymes and Coenzymes).

Keywords for this news article include: Zurich, Europe, Chemicals, Chemistry, Switzerland, Nanoparticle, Nanotechnology, Emerging Technologies, Enzymes and Coenzymes

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Source: Life Science Weekly