News Column

Studies from Nanyang Technological University in the Area of Stem Cells Reported

May 28, 2014

By a News Reporter-Staff News Editor at Biotech Week -- Current study results on Stem Cell Research have been published. According to news reporting originating in Singapore, Singapore, by NewsRx journalists, research stated, "Developments in bioprocessing technology play an important role for overcoming challenges in cardiac tissue engineering. To this end, our laboratory has developed a novel rotary perfused bioreactor for supporting three-dimensional cardiac tissue engineering."

The news reporters obtained a quote from the research from Nanyang Technological University, "The dynamic culture environments provided by our novel perfused rotary bioreactor and/or the high-aspect rotating vessel produced constructs with higher viability and significantly higher cell numbers (up to 4 x 10(5) cells/bead) than static tissue culture flasks. Furthermore, cells in the perfused rotary bioreactor showed earlier gene expressions of cardiac troponin-T, alpha- and beta-myosin heavy chains with higher percentages of cardiac troponin-I-positive cells and better uniformity of sacromeric alpha-actinin expression."

According to the news reporters, the research concluded: "A dynamic and perfused environment, as provided by this bioreactor, provides a superior culture performance in cardiac differentiation for embryonic stem cells particularly for larger 3D constructs."

For more information on this research see: A novel perfused rotary bioreactor for cardiomyogenesis of embryonic stem cells. Biotechnology Letters, 2014;36(5):947-960. Biotechnology Letters can be contacted at: Springer, Van Godewijckstraat 30, 3311 Gz Dordrecht, Netherlands. (Springer -; Biotechnology Letters -

Our news correspondents report that additional information may be obtained by contacting A.L. Teo, Nanyang Technological University, Div Bioengn, Singapore 639798, Singapore. Additional authors for this research include A. Mantalaris, K. Song and M. Lim (see also Stem Cell Research).

Keywords for this news article include: Asia, Tissue Engineering, Biomedical Engineering, Biomedicine, Cardiology, Bioengineering, Stem Cell Research

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Biotech Week

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