News Column

Studies from Mersin University Add New Findings in the Area of Biomedicine and Biomedical Engineering

May 28, 2014

By a News Reporter-Staff News Editor at Biotech Week -- Current study results on Biotechnology have been published. According to news reporting originating in Mersin, Turkey, by NewsRx journalists, research stated, "Bisphenol A (BPA) is an environmental endocrine-disrupting chemicals that is widely used in common consumer products. There is an increasing concern regarding human exposure to BPA owing to the potential adverse effects associated with its estrogenic activity."

The news reporters obtained a quote from the research from Mersin University, "For assessing environmental exposure to BPA, it is essential to have a sensitive, accurate and selective analytical method, especially one that can detect low BPA levels in complex sample matrices. In this study, we developed and validated an accurate, sensitive, and robust liquid chromatography-tandem mass spectrometry method for simultaneous quantification of free BPA and BPA -d-glucuronide (BPA-gluc) concentrations in human urine with only a single injection. Calibration curves were linear over a concentration range of 1-100ng/mL for BPA and 10-1000ng/mL for BPA-gluc. The levels of the analytes were determined quantitatively with HPLC/ESI-MS/MS by using negative electrospray ionization in the select ion monitoring mode and a pentaflouraphenyl propyl column."

According to the news reporters, the research concluded: "The validated method was applied to the analysis of spot urine specimens collected from randomly selected healthy human subjects."

For more information on this research see: Development and validation of an LC-MS/MS method for simultaneous quantitative analysis of free and conjugated bisphenol A in human urine. Biomedical Chromatography, 2014;28(5):686-693. Biomedical Chromatography can be contacted at: Wiley-Blackwell, 111 River St, Hoboken 07030-5774, NJ, USA. (Wiley-Blackwell -; Biomedical Chromatography -

Our news correspondents report that additional information may be obtained by contacting D. Battal, Mersin University, Fac Pharm, Dept. of Pharmacol, TR-33169 Mersin, Turkey. Additional authors for this research include I. Cok, I. Unlusayin and B. Tunctan (see also Biotechnology).

Keywords for this news article include: Biotechnology, Mersin, Turkey, Eurasia

Our reports deliver fact-based news of research and discoveries from around the world. Copyright 2014, NewsRx LLC

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Source: Biotech Week

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